ENSG00000142765


Homo sapiens

Features
Gene ID: ENSG00000142765
  
Biological name :SYTL1
  
Synonyms : Q8IYJ3 / synaptotagmin like 1 / SYTL1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.11
Gene start: 27342020
Gene end: 27353937
  
Corresponding Affymetrix probe sets: 227134_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000316464
Ensembl peptide - ENSP00000440704
Ensembl peptide - ENSP00000481032
Ensembl peptide - ENSP00000484337
Ensembl peptide - ENSP00000420110
NCBI entrez gene - 84958     See in Manteia.
OMIM - 608042
RefSeq - XM_006710991
RefSeq - NM_001193308
RefSeq - NM_032872
RefSeq - XM_005246022
RefSeq - XM_006710990
RefSeq Peptide - NP_001180237
RefSeq Peptide - NP_116261
swissprot - Q5SSC6
swissprot - Q8IYJ3
swissprot - A0A087X1N4
Ensembl - ENSG00000142765
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sytl1ENSDARG00000070094Danio rerio
 Sytl1ENSMUSG00000028860Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SYTL2 / Q9HCH5 / synaptotagmin like 2ENSG0000013750141
SYTL4 / Q96C24 / synaptotagmin like 4ENSG0000010236232
SYTL5 / Q8TDW5 / synaptotagmin like 5ENSG0000014704132
SYTL3 / Q4VX76 / synaptotagmin like 3ENSG0000016467427
RPH3A / Q9Y2J0 / rabphilin 3AENSG0000008916920
DOC2B / double C2 domain betaENSG0000027263616
DOC2A / Q14183 / double C2 domain alphaENSG0000014992716


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR010911  Rab-binding domain
 IPR028378  Synaptotagmin-like protein 1
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006887 exocytosis IDA
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IBA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019897 extrinsic component of plasma membrane ISS
 cellular_componentGO:0031528 microvillus membrane TAS
 cellular_componentGO:0042470 melanosome ISS
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0070382 exocytic vesicle IBA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IBA
 molecular_functionGO:0017137 Rab GTPase binding IEA
 molecular_functionGO:0019905 syntaxin binding IBA
 molecular_functionGO:0030276 clathrin binding IBA
 molecular_functionGO:0042043 neurexin family protein binding ISS


Pathways (from Reactome)
Pathway description
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000099992 Q9BXI6 / TBC1D10A / TBC1 domain family member 10A  / reaction / complex






 

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