ENSDARG00000096249


Danio rerio

Features
Gene ID: ENSDARG00000096249
  
Biological name :ap1m1
  
Synonyms : adaptor-related protein complex 1, mu 1 subunit / ap1m1
  
Possible biological names infered from orthology : AP-1 complex subunit mu-1 / P35585 / Q9BXS5
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 55429988
Gene end: 55492315
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000137784
NCBI entrez gene - 100330411     See in Manteia.
RefSeq - NM_001331127
RefSeq Peptide - NP_001318056
swissprot - A0A0R4IRS1
ZFIN ID - ZDB-GENE-110126-1
Ensembl - ENSDARG00000096249
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AP1M1ENSGALG00000003959Gallus gallus
 AP1M1ENSG00000072958Homo sapiens
 Ap1m1ENSMUSG00000003033Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ap1m3 / adaptor-related protein complex 1, mu 3 subunitENSDARG0000003951279
ap1m2 / adaptor-related protein complex 1, mu 2 subunit / Q9Y6Q5*ENSDARG0000009645477
Q6NWK2 / ap2m1a / ap2m1b / adaptor-related protein complex 2, mu 1 subunit, b / AP2M1* / Q96CW1* / P84091* / AP-2 complex subunit mu * / adaptor related protein complex 2 mu 1 subunit*ENSDARG0000000279040
ap2m1b / adaptor-related protein complex 2, mu 1 subunit, b / AP2M1* / Q96CW1* / P84091* / AP-2 complex subunit mu * / adaptor related protein complex 2 mu 1 subunit*ENSDARG0000003389940
LO018011.1 / AP1M2* / Q9Y6Q5* / adaptor related protein complex 1 mu 2 subunit*ENSDARG0000011393235
ap4m1 / adaptor-related protein complex 4, mu 1 subunit / O00189* / Q9JKC7* / AP-4 complex subunit mu-1 *ENSDARG0000005687130
ap3m1 / adaptor-related protein complex 3, mu 1 subunit / Q9JKC8* / Q9Y2T2* / AP-3 complex subunit mu-1 *ENSDARG0000002992828
ap3m2 / adaptor-related protein complex 3, mu 2 subunit / P53677* / Q8R2R9* / AP-3 complex subunit mu-2 *ENSDARG0000001612827


Protein motifs (from Interpro)
Interpro ID Name
 IPR001392  Clathrin adaptor, mu subunit
 IPR011012  Longin-like domain superfamily
 IPR018240  Clathrin adaptor, mu subunit, conserved site
 IPR022775  AP complex, mu/sigma subunit
 IPR028565  Mu homology domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007420 brain development IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0048565 digestive tract development IGI
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030131 clathrin adaptor complex IEA


Pathways (from Reactome)
Pathway description
MHC class II antigen presentation
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000006 ball ball edematous , abnormal
Show

 ZFA:0000008 brain brain morphology , abnormal
brain apoptotic process increased occurrence , abnormal
Show

 ZFA:0000012 central nervous system central nervous system disorganized , abnormal
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 ZFA:0000029 hindbrain hindbrain morphology , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary morphology , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000079 telencephalon telencephalon morphology , abnormal
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 ZFA:0000101 diencephalon diencephalon morphology , abnormal
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 ZFA:0000123 liver liver morphology , abnormal
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 ZFA:0000128 midbrain midbrain morphology , abnormal
midbrain malformed , abnormal
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 ZFA:0000150 pronephric duct pronephric duct proximal region morphology , abnormal
pronephric duct morphology , abnormal
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 ZFA:0001056 myotome myotome organization quality , abnormal
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 ZFA:0001259 forebrain ventricle forebrain ventricle morphology , abnormal
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 ZFA:0001338 intestine intestine establishment of cell polarity disrupted , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000009087 cd74a / CD74 molecule, major histocompatibility complex, class II invariant chain a / CD74* / P04233* / P04441* / CD74 molecule* / CD74 antigen (invariant polypeptide of major histocompatib...  / complex
 ENSDARG00000027966 ap1s3b / adaptor-related protein complex 1, sigma 3 subunit, b / AP1S3* / Q96PC3* / Q7TN05* / AP-1 complex subunit sigma-3 * / adaptor related protein complex 1 sigma 3 subunit*  / complex
 ENSDARG00000045618 clta / clathrin, light chain A / P09496*  / complex
 ENSDARG00000053122 clvs2 / Q5SPP0 / clavesin 2 / CLVS1* / Q8IUQ0* / clavesin 1*  / complex
 ENSDARG00000056803 ap1s1 / adaptor-related protein complex 1, sigma 1 subunit / P61966* / P61967* / AP-1 complex subunit sigma-1A *  / complex
 ENSDARG00000020621 ap1b1 / adaptor-related protein complex 1, beta 1 subunit / O35643* / Q10567* / Mus musculus adaptor protein complex AP-1, beta 1 subunit (Ap1b1), transcript variant 4, mRNA.*  / complex
 ENSDARG00000090716 cltcb / clathrin, heavy chain b (Hc) / CLTC* / Q00610* / clathrin heavy chain*  / complex
 ENSDARG00000110439 ap1s3a / adaptor-related protein complex 1, sigma 3 subunit, a / AP1S3* / Q96PC3* / adaptor related protein complex 1 sigma 3 subunit*  / complex






 

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