ENSDARG00000097947


Danio rerio

Features
Gene ID: ENSDARG00000097947
  
Biological name :mespbb
  
Synonyms : mesoderm posterior bb / mespbb
  
Possible biological names infered from orthology : mesoderm posterior bHLH transcription factor 1 / mesoderm posterior bHLH transcription factor 2 / Mesoderm posterior protein 1 / MESP1 / MESP2 / P97309 / Q0VG99 / Q9BRJ9
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 11025903
Gene end: 11026907
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000128147
NCBI entrez gene - 100148845     See in Manteia.
swissprot - I2AVW0
ZFIN ID - ZDB-GENE-110609-1
Ensembl - ENSDARG00000097947
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000008275Gallus gallus
 MESP1ENSGALG00000026467Gallus gallus
 MESP1ENSG00000166823Homo sapiens
 MESP2ENSG00000188095Homo sapiens
 Mesp1ENSMUSG00000030544Mus musculus
 Mesp2ENSMUSG00000030543Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mespba / mesoderm posterior ba / MESP1* / MESP2* / Q9BRJ9* / P97309* / Q0VG99* / Mesoderm posterior protein 1 * / mesoderm posterior bHLH transcription factor 2* / mesoderm posterior bHLH t...ENSDARG0000003034736
mespaa / mesoderm posterior aaENSDARG0000001707828
mespab / mesoderm posterior abENSDARG0000006876128
msgn1 / Q90ZL1 / mesogenin 1 / A6NI15* / Q9JK54*ENSDARG0000007054618


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001707 mesoderm formation IBA
 biological_processGO:0001757 somite specification IGI
 biological_processGO:0003007 heart morphogenesis IBA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0032525 somite rostral/caudal axis specification IGI
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048641 regulation of skeletal muscle tissue development IGI
 biological_processGO:0061371 determination of heart left/right asymmetry IGI
 biological_processGO:0097101 blood vessel endothelial cell fate specification IMP
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000028 heart primordium heart primordium right side mislocalised , abnormal
heart primordium absent , abnormal
Show

 ZFA:0000072 somite 1 somite 1 decreased amount , abnormal
somite 1 lacks all parts of type somite border , abnormal
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 ZFA:0000073 somite 5 somite 5 lacks parts or has fewer parts of type somite border , abnormal
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 ZFA:0000155 somite somite shape , abnormal
somite superficial region spatial pattern , abnormal
somite spatial pattern , abnormal
somite decreased amount , abnormal
somite absent , abnormal
Show

 ZFA:0000255 paraxial mesoderm paraxial mesoderm spatial pattern , abnormal
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 ZFA:0000519 hemal arch hemal arch duplicated , abnormal
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 ZFA:0000671 horizontal myoseptum horizontal myoseptum spatial pattern , abnormal
horizontal myoseptum absent , abnormal
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 ZFA:0000728 somite 2 somite 2 lacks all parts of type somite border , abnormal
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 ZFA:0000732 somite 3 somite 3 lacks all parts of type somite border , abnormal
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 ZFA:0000857 somite 4 somite 4 lacks parts or has fewer parts of type somite border , abnormal
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 ZFA:0000944 posterior lateral line posterior lateral line mislocalised ventrally , abnormal
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 ZFA:0001066 neural arch neural arch bifurcated , abnormal
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 ZFA:0001086 muscle pioneer muscle pioneer mislocalised medially , abnormal
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 ZFA:0001462 somite border somite border spatial pattern , abnormal
somite border extracellular matrix organization disrupted , abnormal
somite border extracellular matrix patchy , abnormal
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 ZFA:0005220 larval melanophore stripe larval melanophore stripe spatial pattern , abnormal
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 ZFA:0009116 slow muscle cell slow muscle cell morphology , abnormal
Show

 ZFA:0009199 iridophore iridophore patchy , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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