ENSG00000005379


Homo sapiens

Features
Gene ID: ENSG00000005379
  
Biological name :TSPOAP1
  
Synonyms : O95153 / TSPOAP1 / TSPO associated protein 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q22
Gene start: 58301228
Gene end: 58328760
  
Corresponding Affymetrix probe sets: 205839_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000268893
Ensembl peptide - ENSP00000462518
Ensembl peptide - ENSP00000462710
Ensembl peptide - ENSP00000462822
Ensembl peptide - ENSP00000345824
NCBI entrez gene - 9256     See in Manteia.
OMIM - 610764
RefSeq - XM_017025334
RefSeq - XM_017025327
RefSeq - XM_017025328
RefSeq - XM_017025329
RefSeq - XM_017025330
RefSeq - XM_017025331
RefSeq - XM_017025332
RefSeq - XM_017025333
RefSeq - NM_001261835
RefSeq - NM_004758
RefSeq - NM_024418
RefSeq - XM_005257807
RefSeq - XM_006722173
RefSeq - XM_006722174
RefSeq - XM_006722175
RefSeq - XM_006722176
RefSeq - XM_006722177
RefSeq - XM_006722178
RefSeq - XM_011525472
RefSeq - XM_017025326
RefSeq Peptide - NP_077729
RefSeq Peptide - NP_001248764
RefSeq Peptide - NP_004749
swissprot - A0A0C4DGN5
swissprot - O95153
swissprot - J3KT64
swissprot - J3KSY4
Ensembl - ENSG00000005379
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-105f12.2ENSDARG00000090126Danio rerio
 TSPOAP1ENSGALG00000042533Gallus gallus
 Q7TNF8ENSMUSG00000034156Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UFD9 / RIMBP3 / RIMS binding protein 3ENSG0000027579327
A6NNM3 / RIMBP3B / RIMS binding protein 3BENSG0000027460027
A6NJZ7 / RIMBP3C / RIMS binding protein 3CENSG0000018324627
O15034 / RIMBP2 / RIMS binding protein 2ENSG0000006070922


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR035517  RIMS-binding protein 1
 IPR035753  RIMS-binding protein, second SH3 domain
 IPR035755  RIMS-binding protein, third SH3 domain
 IPR036028  SH3-like domain superfamily
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006700 C21-steroid hormone biosynthetic process TAS
 biological_processGO:0007269 neurotransmitter secretion TAS
 biological_processGO:0008150 biological_process ND
 biological_processGO:0014047 glutamate secretion TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0030156 benzodiazepine receptor binding IEA


Pathways (from Reactome)
Pathway description
Serotonin Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Pregnenolone biosynthesis
Glutamate Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000131626 PPFIA1 / Q13136 / PTPRF interacting protein alpha 1  / complex
 ENSG00000143847 O75335 / PPFIA4 / PTPRF interacting protein alpha 4  / complex
 ENSG00000079841 RIMS1 / Q86UR5 / regulating synaptic membrane exocytosis 1  / complex
 ENSG00000198722 O14795 / UNC13B / unc-13 homolog B  / complex
 ENSG00000100300 TSPO / B1AH88 / P30536 / translocator protein  / complex
 ENSG00000177380 O75145 / PPFIA3 / PTPRF interacting protein alpha 3  / complex
 ENSG00000139220 O75334 / PPFIA2 / PTPRF interacting protein alpha 2  / complex






 

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contact: otassy@igbmc.fr