ENSG00000010327


Homo sapiens

Features
Gene ID: ENSG00000010327
  
Biological name :STAB1
  
Synonyms : Q9NY15 / STAB1 / stabilin 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p21.1
Gene start: 52495338
Gene end: 52524495
  
Corresponding Affymetrix probe sets: 1555319_at (Human Genome U133 Plus 2.0 Array)   1555320_a_at (Human Genome U133 Plus 2.0 Array)   204150_at (Human Genome U133 Plus 2.0 Array)   38487_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000312946
Ensembl peptide - ENSP00000418426
NCBI entrez gene - 23166     See in Manteia.
OMIM - 608560
RefSeq - XM_017006004
RefSeq - NM_015136
RefSeq - XM_017006001
RefSeq - XM_017006002
RefSeq - XM_017006003
RefSeq - XM_005264973
RefSeq - XM_005264974
RefSeq - XM_006713065
RefSeq - XM_017005998
RefSeq - XM_017005999
RefSeq - XM_017006000
RefSeq Peptide - NP_055951
swissprot - Q9NY15
swissprot - H7C4W7
Ensembl - ENSG00000010327
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stab1ENSDARG00000076484Danio rerio
 STAB1ENSGALG00000043672Gallus gallus
 Stab1ENSMUSG00000042286Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STAB2 / Q8WWQ8 / stabilin 2ENSG0000013601140
VCAN / P13611 / versicanENSG0000003842710
ACAN / aggrecanENSG0000015776610
NCAN / O14594 / neurocanENSG000001302879
BCAN / Q96GW7 / brevicanENSG000001326927
HAPLN3 / Q96S86 / hyaluronan and proteoglycan link protein 3ENSG000001405113
HAPLN4 / Q86UW8 / hyaluronan and proteoglycan link protein 4ENSG000001876643
P98066 / TNFAIP6 / TNF alpha induced protein 6ENSG000001236102
HAPLN1 / P10915 / hyaluronan and proteoglycan link protein 1ENSG000001456812
HAPLN2 / Q9GZV7 / hyaluronan and proteoglycan link protein 2ENSG000001327022


Protein motifs (from Interpro)
Interpro ID Name
 IPR000538  Link domain
 IPR000742  EGF-like domain
 IPR000782  FAS1 domain
 IPR001881  EGF-like calcium-binding domain
 IPR002049  Laminin EGF domain
 IPR013032  EGF-like, conserved site
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR024731  EGF domain
 IPR036378  FAS1 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006898 receptor-mediated endocytosis TAS
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007155 cell adhesion NAS
 biological_processGO:0007267 cell-cell signaling IDA
 biological_processGO:0016525 negative regulation of angiogenesis IMP
 biological_processGO:0042742 defense response to bacterium IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 molecular_functionGO:0005041 low-density lipoprotein particle receptor activity IDA
 molecular_functionGO:0005044 scavenger receptor activity IDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005540 hyaluronic acid binding IEA
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity NAS
 molecular_functionGO:0030169 low-density lipoprotein particle binding IDA


Pathways (from Reactome)
Pathway description
Scavenging by Class H Receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000113140 SPARC / P09486 / secreted protein acidic and cysteine rich  / complex / reaction






 

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