ENSG00000042980


Homo sapiens

Features
Gene ID: ENSG00000042980
  
Biological name :ADAM28
  
Synonyms : ADAM28 / ADAM metallopeptidase domain 28 / Q9UKQ2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p21.2
Gene start: 24294040
Gene end: 24359018
  
Corresponding Affymetrix probe sets: 205997_at (Human Genome U133 Plus 2.0 Array)   208268_at (Human Genome U133 Plus 2.0 Array)   208269_s_at (Human Genome U133 Plus 2.0 Array)   241446_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430085
Ensembl peptide - ENSP00000429484
Ensembl peptide - ENSP00000430094
Ensembl peptide - ENSP00000431108
Ensembl peptide - ENSP00000265769
Ensembl peptide - ENSP00000393699
NCBI entrez gene - 10863     See in Manteia.
OMIM - 606188
RefSeq - XM_017012976
RefSeq - XM_006716274
RefSeq - XM_011544367
RefSeq - XM_011544368
RefSeq - XM_011544369
RefSeq - XM_011544370
RefSeq - XM_011544371
RefSeq - XM_017012974
RefSeq - XM_017012975
RefSeq - NM_001304351
RefSeq - NM_014265
RefSeq - NM_021777
RefSeq - XM_005273380
RefSeq - XM_005273382
RefSeq - XM_006716273
RefSeq Peptide - NP_068547
RefSeq Peptide - NP_001291280
RefSeq Peptide - NP_055080
swissprot - E5RJQ1
swissprot - E5RGY1
swissprot - Q9UKQ2
swissprot - H0YBG8
swissprot - H0YBQ8
Ensembl - ENSG00000042980
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adam28ENSDARG00000035514Danio rerio
 Adam28ENSMUSG00000014725Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADAM7 / Q9H2U9 / ADAM metallopeptidase domain 7ENSG0000006920637
ADAM8 / P78325 / ADAM metallopeptidase domain 8ENSG0000015165137
ADAM19 / Q9H013 / ADAM metallopeptidase domain 19ENSG0000013507434
ADAM12 / O43184 / ADAM metallopeptidase domain 12ENSG0000014884831
ADAM33 / Q9BZ11 / ADAM metallopeptidase domain 33ENSG0000014945130
ADAM15 / Q13444 / ADAM metallopeptidase domain 15ENSG0000014353730
ADAM22 / Q9P0K1 / ADAM metallopeptidase domain 22ENSG0000000827726
ADAM11 / O75078 / ADAM metallopeptidase domain 11ENSG0000007367025
ADAM23 / O75077 / ADAM metallopeptidase domain 23ENSG0000011494825


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR001762  Disintegrin domain
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR013032  EGF-like, conserved site
 IPR018358  Disintegrin, conserved site
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR034027  Reprolysin domain, adamalysin-type
 IPR036436  Disintegrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007283 spermatogenesis TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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