ENSG00000149451


Homo sapiens

Features
Gene ID: ENSG00000149451
  
Biological name :ADAM33
  
Synonyms : ADAM33 / ADAM metallopeptidase domain 33 / Q9BZ11
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: p13
Gene start: 3667965
Gene end: 3682246
  
Corresponding Affymetrix probe sets: 232570_s_at (Human Genome U133 Plus 2.0 Array)   233868_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000322550
Ensembl peptide - ENSP00000369190
Ensembl peptide - ENSP00000483343
Ensembl peptide - ENSP00000484600
Ensembl peptide - ENSP00000348912
NCBI entrez gene - 80332     See in Manteia.
OMIM - 607114
RefSeq - XM_017028081
RefSeq - NM_001282447
RefSeq - NM_025220
RefSeq - NM_153202
RefSeq - XM_006723639
RefSeq - XM_006723640
RefSeq - XM_011529366
RefSeq - XM_011529367
RefSeq - XM_011529368
RefSeq - XM_011529370
RefSeq - XM_011529373
RefSeq - XM_005260843
RefSeq Peptide - NP_001269376
RefSeq Peptide - NP_079496
RefSeq Peptide - NP_694882
swissprot - Q08AM2
swissprot - Q08AM3
swissprot - Q9BZ11
swissprot - A2A2L3
Ensembl - ENSG00000149451
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adam19aENSDARG00000059693Danio rerio
 ADAM33ENSGALG00000030602Gallus gallus
 Adam33ENSMUSG00000027318Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADAM19 / Q9H013 / ADAM metallopeptidase domain 19ENSG0000013507444
ADAM12 / O43184 / ADAM metallopeptidase domain 12ENSG0000014884841
ADAM15 / Q13444 / ADAM metallopeptidase domain 15ENSG0000014353738
ADAM8 / P78325 / ADAM metallopeptidase domain 8ENSG0000015165134
ADAM28 / Q9UKQ2 / ADAM metallopeptidase domain 28ENSG0000004298029
ADAM11 / O75078 / ADAM metallopeptidase domain 11ENSG0000007367028
ADAM22 / Q9P0K1 / ADAM metallopeptidase domain 22ENSG0000000827727
ADAM23 / O75077 / ADAM metallopeptidase domain 23ENSG0000011494827
ADAM7 / Q9H2U9 / ADAM metallopeptidase domain 7ENSG0000006920625


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR001762  Disintegrin domain
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR013032  EGF-like, conserved site
 IPR018358  Disintegrin, conserved site
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR034027  Reprolysin domain, adamalysin-type
 IPR036436  Disintegrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 molecular_functionGO:0004222 metalloendopeptidase activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding NAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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