ENSG00000047188


Homo sapiens

Features
Gene ID: ENSG00000047188
  
Biological name :YTHDC2
  
Synonyms : Q9H6S0 / YTHDC2 / YTH domain containing 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q22.2
Gene start: 113513683
Gene end: 113595285
  
Corresponding Affymetrix probe sets: 1568680_s_at (Human Genome U133 Plus 2.0 Array)   205835_s_at (Human Genome U133 Plus 2.0 Array)   205836_s_at (Human Genome U133 Plus 2.0 Array)   213077_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000422916
Ensembl peptide - ENSP00000426644
Ensembl peptide - ENSP00000423101
Ensembl peptide - ENSP00000161863
NCBI entrez gene - 64848     See in Manteia.
OMIM - 616530
RefSeq - XM_017009735
RefSeq - XM_017009730
RefSeq - XM_017009731
RefSeq - XM_017009732
RefSeq - XM_017009733
RefSeq - XM_017009734
RefSeq - NM_022828
RefSeq - XM_011543581
RefSeq - XM_011543582
RefSeq - XM_011543586
RefSeq Peptide - NP_073739
swissprot - D6RF50
swissprot - D6RA70
swissprot - D6R9T8
swissprot - Q9H6S0
Ensembl - ENSG00000047188
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LO017790.1ENSDARG00000103525Danio rerio
 ENSGALG00000000189Gallus gallus
 ENSGALG00000029681Gallus gallus
 B2RR83ENSMUSG00000034653Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DHX57 / Q6P158 / DExH-box helicase 57ENSG0000016321425
DHX9 / Q08211 / DExH-box helicase 9ENSG0000013582924
DHX29 / Q7Z478 / DExH-box helicase 29ENSG0000006724823
DHX36 / Q9H2U1 / DEAH-box helicase 36ENSG0000017495323
DHX30 / Q7L2E3 / DExH-box helicase 30ENSG0000013215320
TDRD9 / Q8NDG6 / tudor domain containing 9ENSG0000015641417


Protein motifs (from Interpro)
Interpro ID Name
 IPR001374  R3H domain
 IPR001650  Helicase, C-terminal
 IPR002110  Ankyrin repeat
 IPR007275  YTH domain
 IPR007502  Helicase-associated domain
 IPR011545  DEAD/DEAH box helicase domain
 IPR011709  Domain of unknown function DUF1605
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR020683  Ankyrin repeat-containing domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031083  ATP-dependent RNA helicase YTHDC2-related
 IPR034083  DExH-box ATP-dependent RNA helicase, R3H domain
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR036867  R3H domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006396 RNA processing IBA
 biological_processGO:0034612 response to tumor necrosis factor IDA
 biological_processGO:0044829 positive regulation by host of viral genome replication IMP
 biological_processGO:0070555 response to interleukin-1 IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008186 RNA-dependent ATPase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0070063 RNA polymerase binding IPI
 molecular_functionGO:1990247 N6-methyladenosine-containing RNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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