ENSG00000048052


Homo sapiens

Features
Gene ID: ENSG00000048052
  
Biological name :HDAC9
  
Synonyms : HDAC9 / histone deacetylase 9 / Q9UKV0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p21.1
Gene start: 18086949
Gene end: 19002416
  
Corresponding Affymetrix probe sets: 1552758_at (Human Genome U133 Plus 2.0 Array)   1552760_at (Human Genome U133 Plus 2.0 Array)   205659_at (Human Genome U133 Plus 2.0 Array)   230968_at (Human Genome U133 Plus 2.0 Array)   234393_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000408617
Ensembl peptide - ENSP00000404763
Ensembl peptide - ENSP00000409003
Ensembl peptide - ENSP00000478829
Ensembl peptide - ENSP00000430036
Ensembl peptide - ENSP00000415095
Ensembl peptide - ENSP00000412497
Ensembl peptide - ENSP00000411422
Ensembl peptide - ENSP00000410337
Ensembl peptide - ENSP00000383912
Ensembl peptide - ENSP00000384017
Ensembl peptide - ENSP00000384382
Ensembl peptide - ENSP00000384657
Ensembl peptide - ENSP00000388568
Ensembl peptide - ENSP00000392564
Ensembl peptide - ENSP00000395655
Ensembl peptide - ENSP00000401669
NCBI entrez gene - 9734     See in Manteia.
OMIM - 606543
RefSeq - XM_017012832
RefSeq - NM_001321876
RefSeq - NM_001321877
RefSeq - NM_001321878
RefSeq - NM_001321879
RefSeq - NM_001321884
RefSeq - NM_001321885
RefSeq - NM_001321886
RefSeq - NM_001321887
RefSeq - NM_001321888
RefSeq - NM_001321889
RefSeq - NM_001321890
RefSeq - NM_001321891
RefSeq - NM_001321893
RefSeq - NM_001321894
RefSeq - NM_001321895
RefSeq - NM_001321896
RefSeq - NM_001321897
RefSeq - NM_001321898
RefSeq - NM_001321899
RefSeq - NM_001321900
RefSeq - NM_001321901
RefSeq - NM_001321902
RefSeq - NM_014707
RefSeq - NM_058176
RefSeq - NM_178423
RefSeq - NM_178425
RefSeq - XM_011515629
RefSeq - XM_011515631
RefSeq - XM_011515634
RefSeq - XM_011515635
RefSeq - XM_011515636
RefSeq - XM_011515637
RefSeq - XM_011515638
RefSeq - XM_011515639
RefSeq - XM_011515641
RefSeq - XM_011515642
RefSeq - XM_011515644
RefSeq - XM_011515645
RefSeq - XM_011515646
RefSeq - XM_011515648
RefSeq - XM_011515649
RefSeq - XM_011515651
RefSeq - XM_017012826
RefSeq - XM_017012827
RefSeq - XM_017012828
RefSeq - XM_017012829
RefSeq - XM_017012830
RefSeq - XM_017012831
RefSeq - NM_001204144
RefSeq - NM_001204145
RefSeq - NM_001204146
RefSeq - NM_001204147
RefSeq - NM_001204148
RefSeq - NM_001321868
RefSeq - NM_001321869
RefSeq - NM_001321870
RefSeq - NM_001321871
RefSeq - NM_001321872
RefSeq - NM_001321873
RefSeq - NM_001321874
RefSeq - NM_001321875
RefSeq Peptide - NP_001191074
RefSeq Peptide - NP_001308828
RefSeq Peptide - NP_001308829
RefSeq Peptide - NP_001308830
RefSeq Peptide - NP_001308831
RefSeq Peptide - NP_055522
RefSeq Peptide - NP_478056
RefSeq Peptide - NP_848510
RefSeq Peptide - NP_848512
RefSeq Peptide - NP_001191073
RefSeq Peptide - NP_001191075
RefSeq Peptide - NP_001191076
RefSeq Peptide - NP_001191077
RefSeq Peptide - NP_001308797
RefSeq Peptide - NP_001308798
RefSeq Peptide - NP_001308799
RefSeq Peptide - NP_001308800
RefSeq Peptide - NP_001308801
RefSeq Peptide - NP_001308802
RefSeq Peptide - NP_001308803
RefSeq Peptide - NP_001308804
RefSeq Peptide - NP_001308805
RefSeq Peptide - NP_001308806
RefSeq Peptide - NP_001308807
RefSeq Peptide - NP_001308808
RefSeq Peptide - NP_001308813
RefSeq Peptide - NP_001308814
RefSeq Peptide - NP_001308815
RefSeq Peptide - NP_001308816
RefSeq Peptide - NP_001308817
RefSeq Peptide - NP_001308818
RefSeq Peptide - NP_001308819
RefSeq Peptide - NP_001308820
RefSeq Peptide - NP_001308822
RefSeq Peptide - NP_001308823
RefSeq Peptide - NP_001308824
RefSeq Peptide - NP_001308825
RefSeq Peptide - NP_001308826
RefSeq Peptide - NP_001308827
swissprot - C9JD56
swissprot - C9J835
swissprot - C9J1W4
swissprot - C9IZS0
swissprot - B7Z3P7
swissprot - F8WDS2
swissprot - C9JLX1
swissprot - Q9UKV0
swissprot - B5MCF1
Ensembl - ENSG00000048052
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hdac9bENSDARG00000056642Danio rerio
 HDAC9ENSGALG00000010854Gallus gallus
 Hdac9ENSMUSG00000004698Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HDAC5 / Q9UQL6 / histone deacetylase 5ENSG0000010884060
HDAC4 / P56524 / histone deacetylase 4ENSG0000006802458
HDAC7 / Q8WUI4 / histone deacetylase 7ENSG0000006127341
HDAC6 / Q9UBN7 / histone deacetylase 6ENSG0000009463124
HDAC10 / Q969S8 / histone deacetylase 10ENSG0000010042912


Protein motifs (from Interpro)
Interpro ID Name
 IPR000286  Histone deacetylase family
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017320  Histone deacetylase class II, eukaryotic
 IPR023696  Ureohydrolase domain superfamily
 IPR023801  Histone deacetylase domain
 IPR024643  Histone deacetylase, glutamine rich N-terminal domain
 IPR037138  Histone deacetylase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001975 response to amphetamine IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0007507 heart development ISS
 biological_processGO:0016575 histone deacetylation IDA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0030183 B cell differentiation TAS
 biological_processGO:0032869 cellular response to insulin stimulus IDA
 biological_processGO:0034983 peptidyl-lysine deacetylation IDA
 biological_processGO:0042113 B cell activation TAS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0048742 regulation of skeletal muscle fiber development ISS
 biological_processGO:0051153 regulation of striated muscle cell differentiation ISS
 biological_processGO:0070932 histone H3 deacetylation IDA
 biological_processGO:0070933 histone H4 deacetylation IDA
 biological_processGO:0090050 positive regulation of cell migration involved in sprouting angiogenesis IMP
 cellular_componentGO:0000118 histone deacetylase complex TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0035097 histone methyltransferase complex ISS
 molecular_functionGO:0003714 transcription corepressor activity ISS
 molecular_functionGO:0004407 histone deacetylase activity IDA
 molecular_functionGO:0005080 protein kinase C binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) IEA
 molecular_functionGO:0033558 protein deacetylase activity IDA
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070491 repressing transcription factor binding ISS


Pathways (from Reactome)
Pathway description
NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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