ENSG00000080293


Homo sapiens

Features
Gene ID: ENSG00000080293
  
Biological name :SCTR
  
Synonyms : P47872 / SCTR / secretin receptor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q14.2
Gene start: 119439843
Gene end: 119525301
  
Corresponding Affymetrix probe sets: 1565737_at (Human Genome U133 Plus 2.0 Array)   1565738_at (Human Genome U133 Plus 2.0 Array)   210382_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000486930
Ensembl peptide - ENSP00000486987
Ensembl peptide - ENSP00000019103
NCBI entrez gene - 6344     See in Manteia.
OMIM - 182098
RefSeq - XM_017004673
RefSeq - XM_011511621
RefSeq - XM_017004670
RefSeq - XM_017004671
RefSeq - XM_017004672
RefSeq - NM_002980
RefSeq - XM_005263730
RefSeq Peptide - NP_002971
swissprot - A0A0D9SFY2
swissprot - A0A0D9SFV7
swissprot - P47872
Ensembl - ENSG00000080293
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SCTRENSDARG00000101077Danio rerio
 SCTRENSGALG00000012106Gallus gallus
 SctrENSMUSG00000026387Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VIPR1 / P32241 / vasoactive intestinal peptide receptor 1ENSG0000011481247
P41586 / ADCYAP1R1 / ADCYAP receptor type IENSG0000007854946
VIPR2 / P41587 / vasoactive intestinal peptide receptor 2ENSG0000010601845
PTH1R / Q03431 / parathyroid hormone 1 receptorENSG0000016080140
GHRHR / Q02643 / growth hormone releasing hormone receptorENSG0000010612839
GLP1R / P43220 / glucagon like peptide 1 receptorENSG0000011216438
GCGR / P47871 / glucagon receptorENSG0000021564438
PTH2R / P49190 / parathyroid hormone 2 receptorENSG0000014440738
GIPR / P48546 / gastric inhibitory polypeptide receptorENSG0000001031037
GLP2R / O95838 / glucagon like peptide 2 receptorENSG0000006532537


Protein motifs (from Interpro)
Interpro ID Name
 IPR000832  GPCR, family 2, secretin-like
 IPR001879  GPCR, family 2, extracellular hormone receptor domain
 IPR002144  GPCR, family 2, secretin receptor
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site
 IPR036445  GPCR family 2, extracellular hormone receptor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0005881 cytoplasmic microtubule IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0015055 secretin receptor activity IDA
 molecular_functionGO:0017046 peptide hormone binding IPI


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Glucagon-type ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000070031 SCT / P09683 / secretin  / complex / reaction






 

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