ENSG00000065325


Homo sapiens

Features
Gene ID: ENSG00000065325
  
Biological name :GLP2R
  
Synonyms : GLP2R / glucagon like peptide 2 receptor / O95838
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p13.1
Gene start: 9822206
Gene end: 9892102
  
Corresponding Affymetrix probe sets: 221312_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000458242
Ensembl peptide - ENSP00000262441
Ensembl peptide - ENSP00000303605
Ensembl peptide - ENSP00000404471
NCBI entrez gene - 9340     See in Manteia.
OMIM - 603659
RefSeq - XM_017025341
RefSeq - NM_004246
RefSeq - XM_005256861
RefSeq - XM_011524077
RefSeq - XM_017025339
RefSeq - XM_017025340
RefSeq Peptide - NP_004237
swissprot - H0Y6C2
swissprot - I3L0P5
swissprot - E9PC86
swissprot - O95838
Ensembl - ENSG00000065325
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GLP2RENSGALG00000041800Gallus gallus
 Glp2rENSMUSG00000049928Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GCGR / P47871 / glucagon receptorENSG0000021564435
GLP1R / P43220 / glucagon like peptide 1 receptorENSG0000011216435
GIPR / P48546 / gastric inhibitory polypeptide receptorENSG0000001031033
SCTR / P47872 / secretin receptorENSG0000008029329
PTH1R / Q03431 / parathyroid hormone 1 receptorENSG0000016080129
VIPR1 / P32241 / vasoactive intestinal peptide receptor 1ENSG0000011481228
VIPR2 / P41587 / vasoactive intestinal peptide receptor 2ENSG0000010601827
PTH2R / P49190 / parathyroid hormone 2 receptorENSG0000014440727
P41586 / ADCYAP1R1 / ADCYAP receptor type IENSG0000007854927
GHRHR / Q02643 / growth hormone releasing hormone receptorENSG0000010612825


Protein motifs (from Interpro)
Interpro ID Name
 IPR000832  GPCR, family 2, secretin-like
 IPR001879  GPCR, family 2, extracellular hormone receptor domain
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site
 IPR036445  GPCR family 2, extracellular hormone receptor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008284 positive regulation of cell proliferation TAS
 biological_processGO:0071377 cellular response to glucagon stimulus IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004967 glucagon receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Glucagon-type ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000115263 GCG / P01275 / glucagon  / complex / reaction






 

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