ENSG00000106018


Homo sapiens

Features
Gene ID: ENSG00000106018
  
Biological name :VIPR2
  
Synonyms : P41587 / vasoactive intestinal peptide receptor 2 / VIPR2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q36.3
Gene start: 159028175
Gene end: 159144957
  
Corresponding Affymetrix probe sets: 205946_at (Human Genome U133 Plus 2.0 Array)   205947_s_at (Human Genome U133 Plus 2.0 Array)   211598_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000384497
Ensembl peptide - ENSP00000402690
Ensembl peptide - ENSP00000262178
Ensembl peptide - ENSP00000366860
NCBI entrez gene - 7434     See in Manteia.
OMIM - 601970
RefSeq - XM_017012580
RefSeq - NM_001304522
RefSeq - NM_001308259
RefSeq - NM_003382
RefSeq - XM_005249561
RefSeq - XM_006716107
RefSeq - XM_006716108
RefSeq - XM_011516550
RefSeq Peptide - NP_001291451
RefSeq Peptide - NP_001295188
RefSeq Peptide - NP_003373
swissprot - E9PCR5
swissprot - C9JCP7
swissprot - P41587
swissprot - X5D7Q6
Ensembl - ENSG00000106018
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vipr2ENSDARG00000012353Danio rerio
 VIPR2ENSGALG00000006575Gallus gallus
 Vipr2ENSMUSG00000011171Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P41586 / ADCYAP1R1 / ADCYAP receptor type IENSG0000007854950
VIPR1 / P32241 / vasoactive intestinal peptide receptor 1ENSG0000011481248
SCTR / P47872 / secretin receptorENSG0000008029345
GHRHR / Q02643 / growth hormone releasing hormone receptorENSG0000010612838
PTH1R / Q03431 / parathyroid hormone 1 receptorENSG0000016080136
GCGR / P47871 / glucagon receptorENSG0000021564435
GLP2R / O95838 / glucagon like peptide 2 receptorENSG0000006532535
GIPR / P48546 / gastric inhibitory polypeptide receptorENSG0000001031034
PTH2R / P49190 / parathyroid hormone 2 receptorENSG0000014440733
GLP1R / P43220 / glucagon like peptide 1 receptorENSG0000011216433


Protein motifs (from Interpro)
Interpro ID Name
 IPR000832  GPCR, family 2, secretin-like
 IPR001571  GPCR, family 2, vasoactive intestinal peptide receptor
 IPR001879  GPCR, family 2, extracellular hormone receptor domain
 IPR002284  GPCR, family 2, vasoactive intestinal peptide receptor 2
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site
 IPR036445  GPCR family 2, extracellular hormone receptor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007190 activation of adenylate cyclase activity IEA
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004999 vasoactive intestinal polypeptide receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Glucagon-type ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000146469 VIP / P01282 / vasoactive intestinal peptide  / complex / reaction






 

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