ENSG00000094755


Homo sapiens

Features
Gene ID: ENSG00000094755
  
Biological name :GABRP
  
Synonyms : GABRP / gamma-aminobutyric acid type A receptor pi subunit / O00591
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q35.1
Gene start: 170763350
Gene end: 170814047
  
Corresponding Affymetrix probe sets: 205044_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000265294
Ensembl peptide - ENSP00000430772
Ensembl peptide - ENSP00000430727
Ensembl peptide - ENSP00000430188
Ensembl peptide - ENSP00000430100
Ensembl peptide - ENSP00000429815
Ensembl peptide - ENSP00000429668
Ensembl peptide - ENSP00000428804
Ensembl peptide - ENSP00000428103
NCBI entrez gene - 2568     See in Manteia.
OMIM - 602729
RefSeq - XM_005265872
RefSeq - NM_001291985
RefSeq - NM_014211
RefSeq Peptide - NP_001278914
RefSeq Peptide - NP_055026
swissprot - E5RG98
swissprot - E5RK74
swissprot - O00591
swissprot - E7EWG0
swissprot - E5RI57
swissprot - E5RHF6
swissprot - E5RHU0
swissprot - E5RGF7
Ensembl - ENSG00000094755
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AL929217.1ENSDARG00000059891Danio rerio
 GABRPENSGALG00000002152Gallus gallus
 GabrpENSMUSG00000020159Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GABRD / O14764 / gamma-aminobutyric acid type A receptor delta subunitENSG0000018773040
GABRB3 / P28472 / gamma-aminobutyric acid type A receptor beta3 subunitENSG0000016620640
GABRB1 / P18505 / gamma-aminobutyric acid type A receptor beta1 subunitENSG0000016328839
GABRB2 / P47870 / gamma-aminobutyric acid type A receptor beta2 subunitENSG0000014586438
GABRR2 / P28476 / gamma-aminobutyric acid type A receptor rho2 subunitENSG0000011188635
GABRR1 / P24046 / gamma-aminobutyric acid type A receptor rho1 subunitENSG0000014627634
A8MPY1 / GABRR3 / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene)ENSG0000018318534
GABRQ / Q9UN88 / gamma-aminobutyric acid type A receptor theta subunitENSG0000026808934
GLRA2 / P23416 / glycine receptor alpha 2ENSG0000010195832
GLRA3 / O75311 / glycine receptor alpha 3ENSG0000014545132
GLRA1 / P23415 / glycine receptor alpha 1ENSG0000014588832
GLRB / P48167 / glycine receptor betaENSG0000010973829
GLRA4 / Q5JXX5 / glycine receptor alpha 4ENSG0000018882829


Protein motifs (from Interpro)
Interpro ID Name
 IPR006028  Gamma-aminobutyric acid A receptor/Glycine receptor alpha
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR008100  Gamma-aminobutyric-acid A receptor pi subunit
 IPR018000  Neurotransmitter-gated ion-channel, conserved site
 IPR036719  Neurotransmitter-gated ion-channel transmembrane domain superfamily
 IPR036734  Neurotransmitter-gated ion-channel ligand-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0034707 chloride channel complex IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:1902711 GABA-A receptor complex IBA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004890 GABA-A receptor activity TAS
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0005254 chloride channel activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr