ENSG00000100739


Homo sapiens

Features
Gene ID: ENSG00000100739
  
Biological name :BDKRB1
  
Synonyms : BDKRB1 / bradykinin receptor B1 / P46663
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q32.2
Gene start: 96255824
Gene end: 96268967
  
Corresponding Affymetrix probe sets: 207510_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000479276
Ensembl peptide - ENSP00000216629
Ensembl peptide - ENSP00000452064
NCBI entrez gene - 623     See in Manteia.
OMIM - 600337
RefSeq - NM_000710
RefSeq Peptide - NP_000701
swissprot - G3V4Y2
swissprot - P46663
Ensembl - ENSG00000100739
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bdkrb1ENSDARG00000020744Danio rerio
 BDKRB1ENSGALG00000020386Gallus gallus
 Bdkrb1ENSMUSG00000041347Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BDKRB2 / P30411 / bradykinin receptor B2ENSG0000016839836
AGTR1 / P30556 / angiotensin II receptor type 1ENSG0000014489128
AGTR2 / P50052 / angiotensin II receptor type 2ENSG0000018077227
GPR15 / P49685 / G protein-coupled receptor 15ENSG0000015416524
ACKR3 / P25106 / atypical chemokine receptor 3ENSG0000014447624
GPR182 / O15218 / G protein-coupled receptor 182ENSG0000016685623
GPR25 / O00155 / G protein-coupled receptor 25ENSG0000017012823
RXFP4 / Q8TDU9 / relaxin/insulin like family peptide receptor 4ENSG0000017308023
RXFP3 / Q9NSD7 / relaxin/insulin like family peptide receptor 3ENSG0000018263123
APLNR / P35414 / apelin receptorENSG0000013481723


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000496  Bradykinin receptor family
 IPR001186  Bradykinin receptor B1
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0002687 positive regulation of leukocyte migration IEA
 biological_processGO:0006950 response to stress IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration TAS
 biological_processGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0009612 response to mechanical stimulus IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0045776 negative regulation of blood pressure IEA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IEA
 cellular_componentGO:0005783 endoplasmic reticulum TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004947 bradykinin receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042277 peptide binding IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000113889 KNG1 / P01042 / kininogen 1  / complex / reaction






 

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