ENSG00000173080


Homo sapiens

Features
Gene ID: ENSG00000173080
  
Biological name :RXFP4
  
Synonyms : Q8TDU9 / relaxin/insulin like family peptide receptor 4 / RXFP4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q22
Gene start: 155941710
Gene end: 155942949
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000357301
NCBI entrez gene - 339403     See in Manteia.
OMIM - 609043
RefSeq - NM_181885
RefSeq Peptide - NP_871001
swissprot - Q8TDU9
Ensembl - ENSG00000173080
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rxfp3.3a1ENSDARG00000069028Danio rerio
 rxfp3.3a2ENSDARG00000062111Danio rerio
 rxfp3.3a3ENSDARG00000069246Danio rerio
 rxfp3.3bENSDARG00000059348Danio rerio
 Rxfp4ENSMUSG00000049741Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RXFP3 / Q9NSD7 / relaxin/insulin like family peptide receptor 3ENSG0000018263139
APLNR / P35414 / apelin receptorENSG0000013481725
GPR25 / O00155 / G protein-coupled receptor 25ENSG0000017012824
AGTR2 / P50052 / angiotensin II receptor type 2ENSG0000018077224
AGTR1 / P30556 / angiotensin II receptor type 1ENSG0000014489122
ACKR3 / P25106 / atypical chemokine receptor 3ENSG0000014447621
BDKRB1 / P46663 / bradykinin receptor B1ENSG0000010073921
BDKRB2 / P30411 / bradykinin receptor B2ENSG0000016839821
GPR182 / O15218 / G protein-coupled receptor 182ENSG0000016685620
GPR15 / P49685 / G protein-coupled receptor 15ENSG0000015416518


Protein motifs (from Interpro)
Interpro ID Name
 IPR000248  Angiotensin II receptor family
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:2000253 positive regulation of feeding behavior IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004966 galanin receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events
Relaxin receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000172410 INSL5 / Q9Y5Q6 / insulin like 5  / complex / reaction
 ENSG00000171136 RLN3 / Q8WXF3 / relaxin 3  / reaction / complex






 

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