ENSG00000182631


Homo sapiens

Features
Gene ID: ENSG00000182631
  
Biological name :RXFP3
  
Synonyms : Q9NSD7 / relaxin/insulin like family peptide receptor 3 / RXFP3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: p13.2
Gene start: 33936386
Gene end: 33938237
  
Corresponding Affymetrix probe sets: 221066_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000328708
NCBI entrez gene - 51289     See in Manteia.
OMIM - 609445
RefSeq - NM_016568
RefSeq Peptide - NP_057652
swissprot - Q9NSD7
Ensembl - ENSG00000182631
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rxfp3ENSDARG00000057410Danio rerio
 RXFP3ENSGALG00000017411Gallus gallus
 Rxfp3ENSMUSG00000060735Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RXFP4 / Q8TDU9 / relaxin/insulin like family peptide receptor 4ENSG0000017308031
AGTR2 / P50052 / angiotensin II receptor type 2ENSG0000018077222
AGTR1 / P30556 / angiotensin II receptor type 1ENSG0000014489121
APLNR / P35414 / apelin receptorENSG0000013481721
ACKR3 / P25106 / atypical chemokine receptor 3ENSG0000014447620
GPR25 / O00155 / G protein-coupled receptor 25ENSG0000017012820
BDKRB2 / P30411 / bradykinin receptor B2ENSG0000016839819
GPR182 / O15218 / G protein-coupled receptor 182ENSG0000016685619
GPR15 / P49685 / G protein-coupled receptor 15ENSG0000015416518
BDKRB1 / P46663 / bradykinin receptor B1ENSG0000010073917


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0032467 positive regulation of cytokinesis IMP
 biological_processGO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0004966 galanin receptor activity IBA
 molecular_functionGO:0008528 G-protein coupled peptide receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events
Relaxin receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000171136 RLN3 / Q8WXF3 / relaxin 3  / complex / reaction






 

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