ENSG00000101180


Homo sapiens

Features
Gene ID: ENSG00000101180
  
Biological name :HRH3
  
Synonyms : histamine receptor H3 / HRH3 / Q9Y5N1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.33
Gene start: 62214970
Gene end: 62220267
  
Corresponding Affymetrix probe sets: 1555215_a_at (Human Genome U133 Plus 2.0 Array)   1555715_a_at (Human Genome U133 Plus 2.0 Array)   220447_at (Human Genome U133 Plus 2.0 Array)   221663_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000321482
Ensembl peptide - ENSP00000482567
Ensembl peptide - ENSP00000342560
NCBI entrez gene - 11255     See in Manteia.
OMIM - 604525
RefSeq - XM_005260266
RefSeq - XM_017027623
RefSeq - NM_007232
RefSeq Peptide - NP_009163
swissprot - Q9Y5N1
swissprot - A0A0A0MR48
swissprot - A0A087WZD3
Ensembl - ENSG00000101180
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hrh3ENSDARG00000035942Danio rerio
 HRH3ENSGALG00000005170Gallus gallus
 Hrh3ENSMUSG00000039059Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HRH4 / Q9H3N8 / histamine receptor H4ENSG0000013448934
CHRM5 / P08912 / cholinergic receptor muscarinic 5ENSG0000018498427
CHRM1 / P11229 / cholinergic receptor muscarinic 1ENSG0000016853927
CHRM3 / P20309 / cholinergic receptor muscarinic 3ENSG0000013301925
CHRM4 / P08173 / cholinergic receptor muscarinic 4ENSG0000018072024
CHRM2 / P08172 / cholinergic receptor muscarinic 2ENSG0000018107223
HRH1 / P35367 / histamine receptor H1ENSG0000019663921


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR003980  Histamine H3 receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001505 regulation of neurotransmitter levels IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007194 negative regulation of adenylate cyclase activity IBA
 biological_processGO:0007269 neurotransmitter secretion TAS
 biological_processGO:0014050 negative regulation of glutamate secretion IBA
 biological_processGO:0014061 regulation of norepinephrine secretion IBA
 biological_processGO:0014063 negative regulation of serotonin secretion IBA
 biological_processGO:0050890 cognition IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004969 histamine receptor activity IEA


Pathways (from Reactome)
Pathway description
Histamine receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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