ENSG00000184984


Homo sapiens

Features
Gene ID: ENSG00000184984
  
Biological name :CHRM5
  
Synonyms : cholinergic receptor muscarinic 5 / CHRM5 / P08912
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q14
Gene start: 33968720
Gene end: 34067457
  
Corresponding Affymetrix probe sets: 221347_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453745
Ensembl peptide - ENSP00000372750
Ensembl peptide - ENSP00000452742
NCBI entrez gene - 1133     See in Manteia.
OMIM - 118496
RefSeq - NM_012125
RefSeq - NM_001320917
RefSeq Peptide - NP_001307846
RefSeq Peptide - NP_036257
swissprot - P08912
swissprot - A0A024R9I2
swissprot - H0YKC0
Ensembl - ENSG00000184984
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chrm5aENSDARG00000099928Danio rerio
 chrm5bENSDARG00000069598Danio rerio
 CHRM5ENSGALG00000009640Gallus gallus
 Chrm5ENSMUSG00000074939Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHRM3 / P20309 / cholinergic receptor muscarinic 3ENSG0000013301953
CHRM1 / P11229 / cholinergic receptor muscarinic 1ENSG0000016853948
CHRM4 / P08173 / cholinergic receptor muscarinic 4ENSG0000018072041
CHRM2 / P08172 / cholinergic receptor muscarinic 2ENSG0000018107238
HRH1 / P35367 / histamine receptor H1ENSG0000019663925
HRH3 / Q9Y5N1 / histamine receptor H3ENSG0000010118023
HRH4 / Q9H3N8 / histamine receptor H4ENSG0000013448920


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000502  Muscarinic acetylcholine receptor M5
 IPR000995  Muscarinic acetylcholine receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001696 gastric acid secretion IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway TAS
 biological_processGO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway IBA
 biological_processGO:0007213 G-protein coupled acetylcholine receptor signaling pathway TAS
 biological_processGO:0007271 synaptic transmission, cholinergic IBA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0015872 dopamine transport IEA
 biological_processGO:0019226 transmission of nerve impulse IEA
 biological_processGO:0060304 regulation of phosphatidylinositol dephosphorylation IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IBA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004435 phosphatidylinositol phospholipase C activity TAS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0016907 G-protein coupled acetylcholine receptor activity IBA


Pathways (from Reactome)
Pathway description
Muscarinic acetylcholine receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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