ENSG00000180720


Homo sapiens

Features
Gene ID: ENSG00000180720
  
Biological name :CHRM4
  
Synonyms : cholinergic receptor muscarinic 4 / CHRM4 / P08173
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p11.2
Gene start: 46385098
Gene end: 46386608
  
Corresponding Affymetrix probe sets: 221357_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000409378
NCBI entrez gene - 1132     See in Manteia.
OMIM - 118495
RefSeq - NM_000741
RefSeq Peptide - NP_000732
swissprot - P08173
Ensembl - ENSG00000180720
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chrm4aENSDARG00000069254Danio rerio
 CHRM4ENSGALG00000008365Gallus gallus
 Chrm4ENSMUSG00000040495Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHRM2 / P08172 / cholinergic receptor muscarinic 2ENSG0000018107257
CHRM5 / P08912 / cholinergic receptor muscarinic 5ENSG0000018498445
CHRM3 / P20309 / cholinergic receptor muscarinic 3ENSG0000013301945
CHRM1 / P11229 / cholinergic receptor muscarinic 1ENSG0000016853942
HRH1 / P35367 / histamine receptor H1ENSG0000019663924
HRH3 / Q9Y5N1 / histamine receptor H3ENSG0000010118022
HRH4 / Q9H3N8 / histamine receptor H4ENSG0000013448918


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000995  Muscarinic acetylcholine receptor family
 IPR001432  Muscarinic acetylcholine receptor M4
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway IEA
 biological_processGO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway IBA
 biological_processGO:0007213 G-protein coupled acetylcholine receptor signaling pathway TAS
 biological_processGO:0007271 synaptic transmission, cholinergic IBA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0040012 regulation of locomotion IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IBA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0016907 G-protein coupled acetylcholine receptor activity IBA


Pathways (from Reactome)
Pathway description
Muscarinic acetylcholine receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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