ENSG00000196639


Homo sapiens

Features
Gene ID: ENSG00000196639
  
Biological name :HRH1
  
Synonyms : histamine receptor H1 / HRH1 / P35367
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p25.3
Gene start: 11137093
Gene end: 11263557
  
Corresponding Affymetrix probe sets: 205579_at (Human Genome U133 Plus 2.0 Array)   205580_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000406705
Ensembl peptide - ENSP00000380247
Ensembl peptide - ENSP00000392383
Ensembl peptide - ENSP00000397028
NCBI entrez gene - 3269     See in Manteia.
OMIM - 600167
RefSeq - XM_017006284
RefSeq - NM_000861
RefSeq - NM_001098211
RefSeq - NM_001098212
RefSeq - NM_001098213
RefSeq - XM_011533652
RefSeq - XM_011533653
RefSeq - XM_017006283
RefSeq Peptide - NP_001091683
RefSeq Peptide - NP_000852
RefSeq Peptide - NP_001091681
RefSeq Peptide - NP_001091682
swissprot - P35367
swissprot - C9J2E6
Ensembl - ENSG00000196639
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HRH1ENSGALG00000004930Gallus gallus
 Hrh1ENSMUSG00000053004Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHRM5 / P08912 / cholinergic receptor muscarinic 5ENSG0000018498427
CHRM1 / P11229 / cholinergic receptor muscarinic 1ENSG0000016853926
CHRM3 / P20309 / cholinergic receptor muscarinic 3ENSG0000013301926
CHRM4 / P08173 / cholinergic receptor muscarinic 4ENSG0000018072024
CHRM2 / P08172 / cholinergic receptor muscarinic 2ENSG0000018107223
HRH3 / Q9Y5N1 / histamine receptor H3ENSG0000010118019
HRH4 / Q9H3N8 / histamine receptor H4ENSG0000013448918


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000921  Histamine H1 receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007613 memory IEA
 biological_processGO:0008542 visual learning IEA
 biological_processGO:0019229 regulation of vasoconstriction IBA
 biological_processGO:0032962 positive regulation of inositol trisphosphate biosynthetic process ISS
 biological_processGO:0043114 regulation of vascular permeability IEA
 biological_processGO:0045907 positive regulation of vasoconstriction IEA
 biological_processGO:0048016 inositol phosphate-mediated signaling ISS
 biological_processGO:0048167 regulation of synaptic plasticity IEA
 biological_processGO:0048245 eosinophil chemotaxis IEA
 biological_processGO:0050804 modulation of chemical synaptic transmission IBA
 biological_processGO:0071420 cellular response to histamine ISS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0004969 histamine receptor activity ISS


Pathways (from Reactome)
Pathway description
Histamine receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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