ENSG00000104221


Homo sapiens

Features
Gene ID: ENSG00000104221
  
Biological name :BRF2
  
Synonyms : BRF2 / BRF2, RNA polymerase III transcription initiation factor subunit / Q9HAW0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: p11.23
Gene start: 37843268
Gene end: 37849904
  
Corresponding Affymetrix probe sets: 218954_s_at (Human Genome U133 Plus 2.0 Array)   218955_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000220659
Ensembl peptide - ENSP00000430193
Ensembl peptide - ENSP00000430107
Ensembl peptide - ENSP00000429554
NCBI entrez gene - 55290     See in Manteia.
OMIM - 607013
RefSeq - NM_018310
RefSeq Peptide - NP_060780
swissprot - E5RGX1
swissprot - E5RGF6
swissprot - Q9HAW0
Ensembl - ENSG00000104221
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 brf2ENSDARG00000002060Danio rerio
 BRF2ENSGALG00000003124Gallus gallus
 Brf2ENSMUSG00000031487Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000812  Transcription factor TFIIB
 IPR013137  Zinc finger, TFIIB-type
 IPR036915  Cyclin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006359 regulation of transcription by RNA polymerase III IMP
 biological_processGO:0034599 cellular response to oxidative stress IMP
 biological_processGO:0070897 DNA-templated transcriptional preinitiation complex assembly IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0001007 obsolete transcription factor activity, RNA polymerase III transcription factor binding IMP
 molecular_functionGO:0001032 RNA polymerase III type 3 promoter DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 3 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000143190 P14859 / POU2F1 / POU class 2 homeobox 1  / complex / reaction
 ENSG00000166478 P52747 / ZNF143 / zinc finger protein 143  / reaction / complex
 ENSG00000112592 TBP / P20226 / TATA-box binding protein  / complex
 ENSG00000145734 BDP1 / A6H8Y1 / B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB  / complex






 

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