ENSG00000166478


Homo sapiens

Features
Gene ID: ENSG00000166478
  
Biological name :ZNF143
  
Synonyms : P52747 / zinc finger protein 143 / ZNF143
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p15.4
Gene start: 9460319
Gene end: 9528524
  
Corresponding Affymetrix probe sets: 221873_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000388628
Ensembl peptide - ENSP00000379849
Ensembl peptide - ENSP00000392323
Ensembl peptide - ENSP00000435881
Ensembl peptide - ENSP00000434922
Ensembl peptide - ENSP00000434638
Ensembl peptide - ENSP00000433743
Ensembl peptide - ENSP00000433221
Ensembl peptide - ENSP00000432154
Ensembl peptide - ENSP00000431306
Ensembl peptide - ENSP00000409432
Ensembl peptide - ENSP00000401493
Ensembl peptide - ENSP00000395221
Ensembl peptide - ENSP00000299606
Ensembl peptide - ENSP00000379843
Ensembl peptide - ENSP00000379847
NCBI entrez gene - 7702     See in Manteia.
OMIM - 603433
RefSeq - XM_017018256
RefSeq - NM_001282656
RefSeq - NM_001282657
RefSeq - NM_003442
RefSeq - XM_005253121
RefSeq - XM_005253122
RefSeq - XM_005253127
RefSeq - XM_011520349
RefSeq - XM_017018252
RefSeq - XM_017018253
RefSeq - XM_017018254
RefSeq - XM_017018255
RefSeq Peptide - NP_001269585
RefSeq Peptide - NP_001269586
RefSeq Peptide - NP_003433
swissprot - E9PS81
swissprot - E9PPB0
swissprot - E9PMY8
swissprot - E9PLS7
swissprot - E9PLN4
swissprot - E9PJF2
swissprot - E7EN86
swissprot - C9JTC5
swissprot - C9JRS3
swissprot - C9JCG1
swissprot - H7C1P6
swissprot - P52747
swissprot - C9J2G7
Ensembl - ENSG00000166478
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q1LYE3ENSDARG00000041581Danio rerio
 znf143aENSDARG00000012887Danio rerio
 ZNF143ENSGALG00000005787Gallus gallus
 O70230ENSMUSG00000061079Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ZNF76 / P36508 / zinc finger protein 76ENSG0000006502953
MTF1 / Q14872 / metal regulatory transcription factor 1ENSG0000018878623
ZXDC / Q2QGD7 / ZXD family zinc finger CENSG0000007047621
ZXDA / P98168 / zinc finger, X-linked, duplicated AENSG0000019820520
ZXDB / P98169 / zinc finger, X-linked, duplicated BENSG0000019845520
Q86VK4 / ZNF410 / zinc finger protein 410ENSG0000011972516
GTF3A / Q92664 / general transcription factor IIIAENSG0000012203412
YY1 / P25490 / YY1 transcription factorENSG0000010081112
YY2 / O15391 / YY2 transcription factorENSG0000023079711
ZFP42 / Q96MM3 / ZFP42 zinc finger proteinENSG0000017905910


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006359 regulation of transcription by RNA polymerase III TAS
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006383 transcription by RNA polymerase III TAS
 biological_processGO:0042795 snRNA transcription by RNA polymerase II TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RNA polymerase II transcribes snRNA genes
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 3 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000104221 BRF2 / Q9HAW0 / BRF2, RNA polymerase III transcription initiation factor subunit  / reaction / complex
 ENSG00000112592 TBP / P20226 / TATA-box binding protein  / reaction / complex
 ENSG00000143190 P14859 / POU2F1 / POU class 2 homeobox 1  / reaction / complex
 ENSG00000185591 SP1 / P08047 / Sp1 transcription factor  / reaction / complex
 ENSG00000028277 P09086 / POU2F2 / POU class 2 homeobox 2  / reaction / complex
 ENSG00000145734 BDP1 / A6H8Y1 / B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr