ENSMUSG00000061079


Mus musculus

Features
Gene ID: ENSMUSG00000061079
  
Biological name :Zfp143
  
Synonyms : O70230 / Zfp143 / zinc finger protein 143
  
Possible biological names infered from orthology : P52747 / ZNF143
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: E3
Gene start: 110061217
Gene end: 110095394
  
Corresponding Affymetrix probe sets: 10556246 (MoGene1.0st)   1422599_s_at (Mouse Genome 430 2.0 Array)   1450681_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000081778
Ensembl peptide - ENSMUSP00000126015
Ensembl peptide - ENSMUSP00000147673
Ensembl peptide - ENSMUSP00000148235
NCBI entrez gene - 20841     See in Manteia.
MGI - MGI:1277969
RefSeq - XM_006507532
RefSeq - NM_009281
RefSeq - XM_006507530
RefSeq - XM_006507531
RefSeq Peptide - NP_033307
swissprot - O70230
Ensembl - ENSMUSG00000061079
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q1LYE3ENSDARG00000041581Danio rerio
 znf143aENSDARG00000012887Danio rerio
 ZNF143ENSGALG00000005787Gallus gallus
 P52747ENSG00000166478Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BMU0 / Zfp523 / zinc finger protein 523 / ZNF76* / P36508* / zinc finger protein 76*ENSMUSG0000002422053
Mtf1 / Q07243 / Metal regulatory transcription factor 1 / Q14872*ENSMUSG0000002889022
Zxdb / A2CE44 / zinc finger, X-linked, duplicated B / ZXDA* / P98169* / P98168* / zinc finger, X-linked, duplicated A*ENSMUSG0000007306220
Zxdc / Q8C8V1 / ZXD family zinc finger C / Q2QGD7*ENSMUSG0000003443020
Q8BKX7 / Zfp410 / zinc finger protein 410 / Q86VK4* / ZNF410*ENSMUSG0000004247216
Gtf3a / transcription factor IIIA / Q92664* / general transcription factor IIIA*ENSMUSG0000001650313
Yy1 / Q00899 / YY1 transcription factor / P25490*ENSMUSG0000002126412
Yy2 / Q3TTC2 / Yy2 transcription factor / O15391*ENSMUSG0000009173611
Zfp42 / zinc finger protein 42 / Q96MM3* / ZFP42 zinc finger protein*ENSMUSG000000511768


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RNA polymerase II transcribes snRNA genes
RNA Polymerase III Transcription Initiation From Type 3 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001924 infertility "inability to produce live offspring" [J:47225]
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Allelic Composition: Hprtb-m3/Y,Impdh2tm1Bmi/Impdh2+
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000014767 Tbp / P29037 / TATA box binding protein / P20226*  / complex / reaction
 ENSMUSG00000049658 Bdp1 / Q571C7 / Transcription factor TFIIIB component B homolog / A6H8Y1* / B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB*  / reaction / complex
 ENSMUSG00000031487 Brf2 / BRF2, RNA polymerase III transcription initiation factor subunit / Q9HAW0*  / complex / reaction
 ENSMUSG00000026565 P25425 / Pou2f1 / POU domain, class 2, transcription factor 1 / P14859* / POU class 2 homeobox 1*  / reaction / complex
 ENSMUSG00000001280 Sp1 / O89090 / Transcription factor Sp1 / P08047* / Sp1 transcription factor*  / complex
 ENSMUSG00000008496 Pou2f2 / Q00196 / POU domain, class 2, transcription factor 2 / P09086* / POU class 2 homeobox 2*  / complex






 

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