ENSG00000122034


Homo sapiens

Features
Gene ID: ENSG00000122034
  
Biological name :GTF3A
  
Synonyms : general transcription factor IIIA / GTF3A / Q92664
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q12.2
Gene start: 27424544
Gene end: 27435823
  
Corresponding Affymetrix probe sets: 201338_x_at (Human Genome U133 Plus 2.0 Array)   215091_s_at (Human Genome U133 Plus 2.0 Array)   238880_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000389655
Ensembl peptide - ENSP00000491190
Ensembl peptide - ENSP00000409175
Ensembl peptide - ENSP00000370532
Ensembl peptide - ENSP00000387806
NCBI entrez gene - 2971     See in Manteia.
OMIM - 600860
RefSeq - NM_002097
RefSeq Peptide - NP_002088
swissprot - H7C326
swissprot - A0A1X7SBT5
swissprot - Q92664
swissprot - H7BZ51
swissprot - H7BZH7
Ensembl - ENSG00000122034
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gtf3aaENSDARG00000030267Danio rerio
 gtf3abENSDARG00000071583Danio rerio
 GTF3AENSGALG00000017098Gallus gallus
 Gtf3aENSMUSG00000016503Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ZXDC / Q2QGD7 / ZXD family zinc finger CENSG0000007047630
ZXDB / P98169 / zinc finger, X-linked, duplicated BENSG0000019845530
ZXDA / P98168 / zinc finger, X-linked, duplicated AENSG0000019820529
ZNF76 / P36508 / zinc finger protein 76ENSG0000006502923
MTF1 / Q14872 / metal regulatory transcription factor 1ENSG0000018878621
P52747 / ZNF143 / zinc finger protein 143ENSG0000016647821
Q86VK4 / ZNF410 / zinc finger protein 410ENSG0000011972518
YY1 / P25490 / YY1 transcription factorENSG0000010081116
YY2 / O15391 / YY2 transcription factorENSG0000023079716
ZFP42 / Q96MM3 / ZFP42 zinc finger proteinENSG0000017905915


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006383 transcription by RNA polymerase III TAS
 biological_processGO:0009303 rRNA transcription TAS
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:0042273 ribosomal large subunit biogenesis IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0008097 5S rRNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000185024 BRF1 / Q92994 / BRF1, RNA polymerase III transcription initiation factor subunit  / complex / reaction
 ENSG00000112592 TBP / P20226 / TATA-box binding protein  / complex / reaction
 ENSG00000145734 BDP1 / A6H8Y1 / B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB  / reaction / complex






 

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