ENSG00000111450


Homo sapiens

Features
Gene ID: ENSG00000111450
  
Biological name :STX2
  
Synonyms : P32856 / STX2 / syntaxin 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.33
Gene start: 130789600
Gene end: 130839266
  
Corresponding Affymetrix probe sets: 207346_at (Human Genome U133 Plus 2.0 Array)   213434_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000261653
Ensembl peptide - ENSP00000342554
Ensembl peptide - ENSP00000376178
NCBI entrez gene - 2054     See in Manteia.
OMIM - 132350
RefSeq - XM_017018989
RefSeq - NM_001980
RefSeq - NM_194356
RefSeq - XM_017018982
RefSeq - XM_017018983
RefSeq - XM_017018984
RefSeq - XM_017018985
RefSeq - XM_005253557
RefSeq - XM_017018978
RefSeq - XM_017018979
RefSeq - XM_017018980
RefSeq - XM_017018981
RefSeq Peptide - NP_001971
RefSeq Peptide - NP_919337
swissprot - P32856
swissprot - J3KNU7
Ensembl - ENSG00000111450
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stx2aENSDARG00000004618Danio rerio
 stx2bENSDARG00000068217Danio rerio
 STX2ENSGALG00000002536Gallus gallus
 Stx2ENSMUSG00000029428Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STX1B / P61266 / syntaxin 1BENSG0000009936564
STX1A / Q16623 / syntaxin 1AENSG0000010608964
STX3 / Q13277 / syntaxin 3ENSG0000016690063
STX4 / Q12846 / syntaxin 4ENSG0000010349644
STX11 / O75558 / syntaxin 11ENSG0000013560431
STX19 / Q8N4C7 / syntaxin 19ENSG0000017875026


Protein motifs (from Interpro)
Interpro ID Name
 IPR000727  Target SNARE coiled-coil homology domain
 IPR006011  Syntaxin, N-terminal domain
 IPR006012  Syntaxin/epimorphin, conserved site
 IPR010989  SNARE
 IPR028671  Syntaxin-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007340 acrosome reaction IEA
 biological_processGO:0007398 ectoderm development TAS
 biological_processGO:0009887 animal organ morphogenesis TAS
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031629 synaptic vesicle fusion to presynaptic active zone membrane IBA
 biological_processGO:0033194 response to hydroperoxide IDA
 biological_processGO:0048278 vesicle docking IBA
 biological_processGO:0051259 protein complex oligomerization IDA
 biological_processGO:1903575 cornified envelope assembly IDA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0008021 synaptic vesicle IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IDA
 cellular_componentGO:0030027 lamellipodium IDA
 cellular_componentGO:0031201 SNARE complex IBA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000149 SNARE binding IBA
 molecular_functionGO:0005484 SNAP receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046983 protein dimerization activity IDA
 molecular_functionGO:0048306 calcium-dependent protein binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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