ENSG00000116396


Homo sapiens

Features
Gene ID: ENSG00000116396
  
Biological name :KCNC4
  
Synonyms : KCNC4 / potassium voltage-gated channel subfamily C member 4 / Q03721
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p13.3
Gene start: 110211343
Gene end: 110283100
  
Corresponding Affymetrix probe sets: 208251_at (Human Genome U133 Plus 2.0 Array)   228436_at (Human Genome U133 Plus 2.0 Array)   235467_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358802
Ensembl peptide - ENSP00000393655
Ensembl peptide - ENSP00000436656
Ensembl peptide - ENSP00000490449
Ensembl peptide - ENSP00000388029
NCBI entrez gene - 3749     See in Manteia.
OMIM - 176265
RefSeq - XM_011541404
RefSeq - NM_004978
RefSeq - XM_006710627
RefSeq - XM_011541401
RefSeq - XM_011541402
RefSeq - XM_011541403
RefSeq - NM_001039574
RefSeq Peptide - NP_001034663
RefSeq Peptide - NP_004969
swissprot - H7BZ66
swissprot - Q03721
swissprot - A0A1B0GVB7
Ensembl - ENSG00000116396
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnc4ENSDARG00000061288Danio rerio
 ENSGALG00000000400Gallus gallus
 ENSGALG00000033853Gallus gallus
 Kcnc4ENSMUSG00000027895Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNC3 / Q14003 / potassium voltage-gated channel subfamily C member 3ENSG0000013139866
KCNC2 / Q96PR1 / potassium voltage-gated channel subfamily C member 2ENSG0000016600666
KCNC1 / P48547 / potassium voltage-gated channel subfamily C member 1ENSG0000012915965
KCNA1 / Q09470 / potassium voltage-gated channel subfamily A member 1ENSG0000011126229
KCNA2 / P16389 / potassium voltage-gated channel subfamily A member 2ENSG0000017730129
KCNA7 / Q96RP8 / potassium voltage-gated channel subfamily A member 7ENSG0000010484829
KCNA4 / P22459 / potassium voltage-gated channel subfamily A member 4ENSG0000018225529
KCNA3 / P22001 / potassium voltage-gated channel subfamily A member 3ENSG0000017727229
KCNA5 / P22460 / potassium voltage-gated channel subfamily A member 5ENSG0000013003728
KCNA10 / Q16322 / potassium voltage-gated channel subfamily A member 10ENSG0000014310527
KCNA6 / P17658 / potassium voltage-gated channel subfamily A member 6ENSG0000015107927
KCND3 / Q9UK17 / potassium voltage-gated channel subfamily D member 3ENSG0000017138527
KCND2 / Q9NZV8 / potassium voltage-gated channel subfamily D member 2ENSG0000018440826
KCND1 / Q9NSA2 / potassium voltage-gated channel subfamily D member 1ENSG0000010205726


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003974  Potassium channel, voltage dependent, Kv3
 IPR005405  Potassium channel, voltage dependent, Kv3.4
 IPR005821  Ion transport domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR021105  Potassium channel, voltage dependent, Kv3, inactivation domain
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0046928 regulation of neurotransmitter secretion IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0031594 neuromuscular junction IEA
 cellular_componentGO:0043679 axon terminus IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005267 potassium channel activity TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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