ENSG00000177272


Homo sapiens

Features
Gene ID: ENSG00000177272
  
Biological name :KCNA3
  
Synonyms : KCNA3 / P22001 / potassium voltage-gated channel subfamily A member 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p13.3
Gene start: 110672465
Gene end: 110675033
  
Corresponding Affymetrix probe sets: 207237_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358784
NCBI entrez gene - 3738     See in Manteia.
OMIM - 176263
RefSeq - NM_002232
RefSeq Peptide - NP_002223
swissprot - P22001
Ensembl - ENSG00000177272
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCNA3ENSGALG00000036942Gallus gallus
 Kcna3ENSMUSG00000047959Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNA2 / P16389 / potassium voltage-gated channel subfamily A member 2ENSG0000017730167
KCNA1 / Q09470 / potassium voltage-gated channel subfamily A member 1ENSG0000011126265
KCNA4 / P22459 / potassium voltage-gated channel subfamily A member 4ENSG0000018225561
KCNA5 / P22460 / potassium voltage-gated channel subfamily A member 5ENSG0000013003760
KCNA6 / P17658 / potassium voltage-gated channel subfamily A member 6ENSG0000015107959
KCNA10 / Q16322 / potassium voltage-gated channel subfamily A member 10ENSG0000014310552
KCNA7 / Q96RP8 / potassium voltage-gated channel subfamily A member 7ENSG0000010484852
KCNC3 / Q14003 / potassium voltage-gated channel subfamily C member 3ENSG0000013139832
KCNC2 / Q96PR1 / potassium voltage-gated channel subfamily C member 2ENSG0000016600632
KCNC4 / Q03721 / potassium voltage-gated channel subfamily C member 4ENSG0000011639632
KCNC1 / P48547 / potassium voltage-gated channel subfamily C member 1ENSG0000012915931
KCND1 / Q9NSA2 / potassium voltage-gated channel subfamily D member 1ENSG0000010205730
KCND2 / Q9NZV8 / potassium voltage-gated channel subfamily D member 2ENSG0000018440830
KCND3 / Q9UK17 / potassium voltage-gated channel subfamily D member 3ENSG0000017138529


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003972  Potassium channel, voltage dependent, Kv1
 IPR004050  Potassium channel, voltage dependent, Kv1.3
 IPR005821  Ion transport domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport TAS
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity TAS
 molecular_functionGO:0005249 voltage-gated potassium channel activity IBA
 molecular_functionGO:0005251 delayed rectifier potassium channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015271 outward rectifier potassium channel activity IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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