ENSG00000182255


Homo sapiens

Features
Gene ID: ENSG00000182255
  
Biological name :KCNA4
  
Synonyms : KCNA4 / P22459 / potassium voltage-gated channel subfamily A member 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p14.1
Gene start: 30009741
Gene end: 30017023
  
Corresponding Affymetrix probe sets: 207248_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000328511
NCBI entrez gene - 3739     See in Manteia.
OMIM - 176266
RefSeq - NM_002233
RefSeq Peptide - NP_002224
swissprot - P22459
Ensembl - ENSG00000182255
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcna4ENSDARG00000078650Danio rerio
 KCNA4ENSGALG00000012142Gallus gallus
 Kcna4ENSMUSG00000042604Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNA5 / P22460 / potassium voltage-gated channel subfamily A member 5ENSG0000013003753
KCNA3 / P22001 / potassium voltage-gated channel subfamily A member 3ENSG0000017727253
KCNA2 / P16389 / potassium voltage-gated channel subfamily A member 2ENSG0000017730153
KCNA1 / Q09470 / potassium voltage-gated channel subfamily A member 1ENSG0000011126252
KCNA6 / P17658 / potassium voltage-gated channel subfamily A member 6ENSG0000015107949
KCNA10 / Q16322 / potassium voltage-gated channel subfamily A member 10ENSG0000014310546
KCNA7 / Q96RP8 / potassium voltage-gated channel subfamily A member 7ENSG0000010484844
KCNC2 / Q96PR1 / potassium voltage-gated channel subfamily C member 2ENSG0000016600628
KCNC3 / Q14003 / potassium voltage-gated channel subfamily C member 3ENSG0000013139828
KCNC4 / Q03721 / potassium voltage-gated channel subfamily C member 4ENSG0000011639628
KCNC1 / P48547 / potassium voltage-gated channel subfamily C member 1ENSG0000012915927
KCND1 / Q9NSA2 / potassium voltage-gated channel subfamily D member 1ENSG0000010205727
KCND2 / Q9NZV8 / potassium voltage-gated channel subfamily D member 2ENSG0000018440826
KCND3 / Q9UK17 / potassium voltage-gated channel subfamily D member 3ENSG0000017138525


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003972  Potassium channel, voltage dependent, Kv1
 IPR005821  Ion transport domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR012897  Potassium channel, voltage dependent, Kv1.4, tandem inactivation domain
 IPR020467  Potassium channel, voltage dependent, Kv1.4
 IPR028325  Voltage-gated potassium channel
 IPR037065  Potassium channel, voltage dependent, Kv1.4, tandem inactivation domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport TAS
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IMP
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IMP
 cellular_componentGO:0008076 voltage-gated potassium channel complex ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity TAS
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030955 potassium ion binding IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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