ENSG00000124171


Homo sapiens

Features
Gene ID: ENSG00000124171
  
Biological name :PARD6B
  
Synonyms : par-6 family cell polarity regulator beta / PARD6B / Q9BYG5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q13.13
Gene start: 50731544
Gene end: 50756795
  
Corresponding Affymetrix probe sets: 211907_s_at (Human Genome U133 Plus 2.0 Array)   214827_at (Human Genome U133 Plus 2.0 Array)   235165_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000379354
Ensembl peptide - ENSP00000360672
NCBI entrez gene - 84612     See in Manteia.
OMIM - 608975
RefSeq - NM_032521
RefSeq Peptide - NP_115910
swissprot - Q9BYG5
Ensembl - ENSG00000124171
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pard6bENSDARG00000003865Danio rerio
 PARD6BENSGALG00000007994Gallus gallus
 Pard6bENSMUSG00000044641Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PARD6G / Q9BYG4 / par-6 family cell polarity regulator gammaENSG0000017818456
PARD6A / Q9NPB6 / par-6 family cell polarity regulator alphaENSG0000010298147


Protein motifs (from Interpro)
Interpro ID Name
 IPR000270  PB1 domain
 IPR001478  PDZ domain
 IPR034868  Partitioning defective protein 6, PB1 domain
 IPR034873  Partitioning defective 6 homologue beta
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007043 cell-cell junction assembly TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007163 establishment or maintenance of cell polarity TAS
 biological_processGO:0007409 axonogenesis TAS
 biological_processGO:0030334 regulation of cell migration TAS
 biological_processGO:0051301 cell division IEA
 biological_processGO:0065003 protein-containing complex assembly IDA
 biological_processGO:0070830 bicellular tight junction assembly TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045177 apical part of cell IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Tight junction interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000163558 PRKCI / P41743 / protein kinase C iota  / complex
 ENSG00000158769 F11R / Q9Y624 / F11 receptor  / complex / reaction
 ENSG00000148498 PARD3 / Q8TEW0 / par-3 family cell polarity regulator  / complex






 

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