ENSG00000126107


Homo sapiens

Features
Gene ID: ENSG00000126107
  
Biological name :HECTD3
  
Synonyms : HECTD3 / HECT domain E3 ubiquitin protein ligase 3 / Q5T447
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p34.1
Gene start: 45002540
Gene end: 45011329
  
Corresponding Affymetrix probe sets: 218632_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361241
Ensembl peptide - ENSP00000361245
NCBI entrez gene - 79654     See in Manteia.
RefSeq - NM_024602
RefSeq - XM_011542140
RefSeq Peptide - NP_078878
swissprot - Q5T447
Ensembl - ENSG00000126107
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hectd3ENSDARG00000038905Danio rerio
 ENSGALG00000010203Gallus gallus
 ENSGALG00000010217Gallus gallus
 Hectd3ENSMUSG00000046861Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HERC2 / O95714 / HECT and RLD domain containing E3 ubiquitin protein ligase 2ENSG0000012873120
HERC1 / Q15751 / HECT and RLD domain containing E3 ubiquitin protein ligase family member 1ENSG0000010365719
HERC6 / Q8IVU3 / HECT and RLD domain containing E3 ubiquitin protein ligase family member 6ENSG0000013864218
HERC3 / Q15034 / HECT and RLD domain containing E3 ubiquitin protein ligase 3ENSG0000013864117
HERC4 / Q5GLZ8 / HECT and RLD domain containing E3 ubiquitin protein ligase 4ENSG0000014863416
HERC5 / Q9UII4 / HECT and RLD domain containing E3 ubiquitin protein ligase 5ENSG0000013864615
UBE3A / Q05086 / ubiquitin protein ligase E3AENSG0000011406214
HECTD2 / Q5U5R9 / HECT domain E3 ubiquitin protein ligase 2ENSG0000016533813
RCCD1 / A6NED2 / RCC1 domain containing 1ENSG000001669655
AC098582.1ENSG000002853851


Protein motifs (from Interpro)
Interpro ID Name
 IPR000569  HECT domain
 IPR004939  APC10/DOC domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR035983  HECT, E3 ligase catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019905 syntaxin binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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