ENSG00000138641


Homo sapiens

Features
Gene ID: ENSG00000138641
  
Biological name :HERC3
  
Synonyms : HECT and RLD domain containing E3 ubiquitin protein ligase 3 / HERC3 / Q15034
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q22.1
Gene start: 88592423
Gene end: 88708542
  
Corresponding Affymetrix probe sets: 1554290_at (Human Genome U133 Plus 2.0 Array)   206183_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000389991
Ensembl peptide - ENSP00000385684
Ensembl peptide - ENSP00000405863
Ensembl peptide - ENSP00000421021
Ensembl peptide - ENSP00000410029
Ensembl peptide - ENSP00000406210
Ensembl peptide - ENSP00000264345
Ensembl peptide - ENSP00000384005
NCBI entrez gene - 8916     See in Manteia.
OMIM - 605200
RefSeq - XM_017008808
RefSeq - NM_001318505
RefSeq - NM_014606
RefSeq - XM_005263327
RefSeq - XM_005263329
RefSeq - XM_005263330
RefSeq - XM_005263331
RefSeq - XM_005263332
RefSeq - XM_017008806
RefSeq - XM_017008807
RefSeq - NM_001271602
RefSeq Peptide - NP_001305434
RefSeq Peptide - NP_055421
RefSeq Peptide - NP_001258531
swissprot - H0Y8G9
swissprot - C9JKA7
swissprot - Q15034
swissprot - C9J6Z1
swissprot - C9JFL2
swissprot - C9J8E7
Ensembl - ENSG00000138641
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 herc3ENSDARG00000075887Danio rerio
 HERC3ENSGALG00000010363Gallus gallus
 Herc3ENSMUSG00000029804Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HERC4 / Q5GLZ8 / HECT and RLD domain containing E3 ubiquitin protein ligase 4ENSG0000014863456
HERC6 / Q8IVU3 / HECT and RLD domain containing E3 ubiquitin protein ligase family member 6ENSG0000013864237
HERC5 / Q9UII4 / HECT and RLD domain containing E3 ubiquitin protein ligase 5ENSG0000013864634
HECTD2 / Q5U5R9 / HECT domain E3 ubiquitin protein ligase 2ENSG0000016533821
HERC2 / O95714 / HECT and RLD domain containing E3 ubiquitin protein ligase 2ENSG0000012873120
HERC1 / Q15751 / HECT and RLD domain containing E3 ubiquitin protein ligase family member 1ENSG0000010365720
UBE3A / Q05086 / ubiquitin protein ligase E3AENSG0000011406220
HECTD3 / Q5T447 / HECT domain E3 ubiquitin protein ligase 3ENSG0000012610714
RCCD1 / A6NED2 / RCC1 domain containing 1ENSG000001669658
AC098582.1ENSG000002853857


Protein motifs (from Interpro)
Interpro ID Name
 IPR000408  Regulator of chromosome condensation, RCC1
 IPR000569  HECT domain
 IPR009091  Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
 IPR035983  HECT, E3 ligase catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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