ENSG00000165338


Homo sapiens

Features
Gene ID: ENSG00000165338
  
Biological name :HECTD2
  
Synonyms : HECTD2 / HECT domain E3 ubiquitin protein ligase 2 / Q5U5R9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q23.32
Gene start: 91409280
Gene end: 91514829
  
Corresponding Affymetrix probe sets: 1565698_at (Human Genome U133 Plus 2.0 Array)   1565699_at (Human Genome U133 Plus 2.0 Array)   227568_at (Human Genome U133 Plus 2.0 Array)   238803_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000401023
Ensembl peptide - ENSP00000487686
Ensembl peptide - ENSP00000298068
Ensembl peptide - ENSP00000360731
Ensembl peptide - ENSP00000360746
NCBI entrez gene - 143279     See in Manteia.
RefSeq - XM_017015752
RefSeq - NM_001284274
RefSeq - NM_001348365
RefSeq - NM_173497
RefSeq - NM_182765
RefSeq - XM_017015750
RefSeq Peptide - NP_001271203
RefSeq Peptide - NP_001335294
RefSeq Peptide - NP_775768
RefSeq Peptide - NP_877497
swissprot - A0A0J9YVV1
swissprot - Q5U5R9
swissprot - X6R824
swissprot - E7ERR3
Ensembl - ENSG00000165338
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hectd2ENSDARG00000061194Danio rerio
 HECTD2ENSGALG00000038043Gallus gallus
 Hectd2ENSMUSG00000041180Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UBE3A / Q05086 / ubiquitin protein ligase E3AENSG0000011406230
HERC4 / Q5GLZ8 / HECT and RLD domain containing E3 ubiquitin protein ligase 4ENSG0000014863429
HERC3 / Q15034 / HECT and RLD domain containing E3 ubiquitin protein ligase 3ENSG0000013864128
HERC5 / Q9UII4 / HECT and RLD domain containing E3 ubiquitin protein ligase 5ENSG0000013864622
HERC6 / Q8IVU3 / HECT and RLD domain containing E3 ubiquitin protein ligase family member 6ENSG0000013864220
HERC2 / O95714 / HECT and RLD domain containing E3 ubiquitin protein ligase 2ENSG0000012873115
HERC1 / Q15751 / HECT and RLD domain containing E3 ubiquitin protein ligase family member 1ENSG0000010365714
HECTD3 / Q5T447 / HECT domain E3 ubiquitin protein ligase 3ENSG0000012610714
RCCD1 / A6NED2 / RCC1 domain containing 1ENSG000001669653
AC098582.1ENSG000002853850


Protein motifs (from Interpro)
Interpro ID Name
 IPR000569  HECT domain
 IPR035983  HECT, E3 ligase catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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