ENSG00000127951


Homo sapiens

Features
Gene ID: ENSG00000127951
  
Biological name :FGL2
  
Synonyms : FGL2 / fibrinogen like 2 / Q14314
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q11.23
Gene start: 77193371
Gene end: 77199848
  
Corresponding Affymetrix probe sets: 204834_at (Human Genome U133 Plus 2.0 Array)   227265_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000248598
Ensembl peptide - ENSP00000490549
NCBI entrez gene - 10875     See in Manteia.
OMIM - 605351
RefSeq - NM_006682
RefSeq Peptide - NP_006673
swissprot - A4D1B8
swissprot - A0A1B0GVK0
swissprot - Q14314
Ensembl - ENSG00000127951
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgl2aENSDARG00000019861Danio rerio
 fgl2bENSDARG00000019686Danio rerio
 FGL2ENSGALG00000008306Gallus gallus
 Fgl2ENSMUSG00000039899Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ANGPT1 / Q15389 / angiopoietin 1ENSG0000015418828
ANGPT2 / O15123 / angiopoietin 2ENSG0000009187928
O43827 / ANGPTL7 / angiopoietin like 7ENSG0000017181927
ANGPT4 / Q9Y264 / angiopoietin 4ENSG0000010128026
Q8NI99 / ANGPTL6 / angiopoietin like 6ENSG0000013081225
O95841 / ANGPTL1 / angiopoietin like 1ENSG0000011619425
FIBCD1 / Q8N539 / fibrinogen C domain containing 1ENSG0000013072025
Q9UKU9 / ANGPTL2 / angiopoietin like 2ENSG0000013685924
FCN1 / O00602 / ficolin 1ENSG0000008526523
FCN2 / Q15485 / ficolin 2ENSG0000016033923
MFAP4 / P55083 / microfibril associated protein 4ENSG0000016648221
FCN3 / O75636 / ficolin 3ENSG0000014274821


Protein motifs (from Interpro)
Interpro ID Name
 IPR002181  Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
 IPR014715  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2
 IPR014716  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
 IPR020837  Fibrinogen, conserved site
 IPR033083  Fibroleukin
 IPR036056  Fibrinogen-like, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005577 fibrinogen complex TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0008233 peptidase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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