ENSG00000129654


Homo sapiens

Features
Gene ID: ENSG00000129654
  
Biological name :FOXJ1
  
Synonyms : forkhead box J1 / FOXJ1 / Q92949
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q25.1
Gene start: 76136333
Gene end: 76141299
  
Corresponding Affymetrix probe sets: 205906_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000323880
NCBI entrez gene - 2302     See in Manteia.
OMIM - 602291
RefSeq - NM_001454
RefSeq Peptide - NP_001445
swissprot - A0A024R8P1
swissprot - Q92949
Ensembl - ENSG00000129654
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F1QDF8ENSDARG00000101919Danio rerio
 FOXJ1ENSGALG00000041025Gallus gallus
 Foxj1ENSMUSG00000034227Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOXK2 / Q01167 / forkhead box K2ENSG0000014156823
FOXJ2 / Q9P0K8 / forkhead box J2ENSG0000006597022
FOXJ3 / Q9UPW0 / forkhead box J3ENSG0000019881522
FOXN4 / Q96NZ1 / forkhead box N4ENSG0000013944521
FOXK1 / P85037 / forkhead box K1ENSG0000016491621
FOXN3 / O00409 / forkhead box N3ENSG0000005325420
FOXN1 / O15353 / forkhead box N1ENSG0000010910119
FOXN2 / P32314 / forkhead box N2ENSG0000017080218


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0002508 central tolerance induction ISS
 biological_processGO:0002635 negative regulation of germinal center formation ISS
 biological_processGO:0002897 positive regulation of central B cell tolerance induction ISS
 biological_processGO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006959 humoral immune response ISS
 biological_processGO:0007283 spermatogenesis NAS
 biological_processGO:0007368 determination of left/right symmetry IEA
 biological_processGO:0007389 pattern specification process ISS
 biological_processGO:0007420 brain development NAS
 biological_processGO:0007507 heart development IEA
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0030036 actin cytoskeleton organization ISS
 biological_processGO:0030856 regulation of epithelial cell differentiation IEA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity ISS
 biological_processGO:0033085 negative regulation of T cell differentiation in thymus ISS
 biological_processGO:0035089 establishment of apical/basal cell polarity ISS
 biological_processGO:0035502 metanephric part of ureteric bud development IEP
 biological_processGO:0042130 negative regulation of T cell proliferation IEA
 biological_processGO:0044458 motile cilium assembly IEA
 biological_processGO:0045409 negative regulation of interleukin-6 biosynthetic process ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0050869 negative regulation of B cell activation ISS
 biological_processGO:0050900 leukocyte migration ISS
 biological_processGO:0060271 cilium assembly ISS
 biological_processGO:0060428 lung epithelium development NAS
 biological_processGO:0060429 epithelium development ISS
 biological_processGO:0060972 left/right pattern formation IEA
 biological_processGO:0072016 glomerular parietal epithelial cell development IEP
 biological_processGO:0090630 activation of GTPase activity ISS
 biological_processGO:1901248 positive regulation of lung ciliated cell differentiation IDA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISS
 molecular_functionGO:0003677 DNA binding NAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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