ENSG00000170802


Homo sapiens

Features
Gene ID: ENSG00000170802
  
Biological name :FOXN2
  
Synonyms : forkhead box N2 / FOXN2 / P32314
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p16.3
Gene start: 48314637
Gene end: 48379294
  
Corresponding Affymetrix probe sets: 206708_at (Human Genome U133 Plus 2.0 Array)   226711_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000388486
Ensembl peptide - ENSP00000484534
Ensembl peptide - ENSP00000343633
NCBI entrez gene - 3344     See in Manteia.
OMIM - 143089
RefSeq - XM_017003959
RefSeq - XM_011532808
RefSeq - XM_017003956
RefSeq - XM_017003957
RefSeq - XM_017003958
RefSeq - NM_002158
RefSeq - XM_005264282
RefSeq - XM_005264283
RefSeq - XM_006712001
RefSeq - XM_006712002
RefSeq Peptide - NP_002149
swissprot - C9JTA7
swissprot - A0A087X1X6
swissprot - P32314
Ensembl - ENSG00000170802
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 forkhead box N2ENSDARG00000055574Danio rerio
 foxn2bENSDARG00000045105Danio rerio
 FOXN2ENSGALG00000008942Gallus gallus
 Foxn2ENSMUSG00000034998Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOXN3 / O00409 / forkhead box N3ENSG0000005325450
FOXJ3 / Q9UPW0 / forkhead box J3ENSG0000019881523
FOXK2 / Q01167 / forkhead box K2ENSG0000014156822
FOXK1 / P85037 / forkhead box K1ENSG0000016491621
FOXN1 / O15353 / forkhead box N1ENSG0000010910120
FOXN4 / Q96NZ1 / forkhead box N4ENSG0000013944520
FOXJ2 / Q9P0K8 / forkhead box J2ENSG0000006597020
FOXJ1 / Q92949 / forkhead box J1ENSG0000012965418


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IBA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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