ENSG00000053254


Homo sapiens

Features
Gene ID: ENSG00000053254
  
Biological name :FOXN3
  
Synonyms : forkhead box N3 / FOXN3 / O00409
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q32.11
Gene start: 89124871
Gene end: 89619149
  
Corresponding Affymetrix probe sets: 205021_s_at (Human Genome U133 Plus 2.0 Array)   205022_s_at (Human Genome U133 Plus 2.0 Array)   218031_s_at (Human Genome U133 Plus 2.0 Array)   222494_at (Human Genome U133 Plus 2.0 Array)   229652_s_at (Human Genome U133 Plus 2.0 Array)   241984_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000452290
Ensembl peptide - ENSP00000479114
Ensembl peptide - ENSP00000452444
Ensembl peptide - ENSP00000261302
Ensembl peptide - ENSP00000343288
Ensembl peptide - ENSP00000450684
Ensembl peptide - ENSP00000450783
Ensembl peptide - ENSP00000450833
Ensembl peptide - ENSP00000451024
Ensembl peptide - ENSP00000451135
Ensembl peptide - ENSP00000451437
Ensembl peptide - ENSP00000451902
Ensembl peptide - ENSP00000452005
Ensembl peptide - ENSP00000452227
NCBI entrez gene - 1112     See in Manteia.
OMIM - 602628
RefSeq - NM_001085471
RefSeq - NM_005197
RefSeq Peptide - NP_001078940
RefSeq Peptide - NP_005188
swissprot - H0YJ43
swissprot - H0YJ54
swissprot - H0YJ94
swissprot - H0YJG3
swissprot - H0YJY0
swissprot - A0A024R6I1
swissprot - O00409
swissprot - G3V3A7
swissprot - G3V4N5
swissprot - G3V5C7
swissprot - H0YJ22
Ensembl - ENSG00000053254
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxn3ENSDARG00000012833Danio rerio
 FOXN3ENSGALG00000010665Gallus gallus
 Foxn3ENSMUSG00000033713Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOXN2 / P32314 / forkhead box N2ENSG0000017080244
FOXK2 / Q01167 / forkhead box K2ENSG0000014156821
FOXJ2 / Q9P0K8 / forkhead box J2ENSG0000006597020
FOXJ3 / Q9UPW0 / forkhead box J3ENSG0000019881520
FOXN1 / O15353 / forkhead box N1ENSG0000010910120
FOXK1 / P85037 / forkhead box K1ENSG0000016491620
FOXN4 / Q96NZ1 / forkhead box N4ENSG0000013944519
FOXJ1 / Q92949 / forkhead box J1ENSG0000012965418


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007095 mitotic G2 DNA damage checkpoint IGI
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IBA
 biological_processGO:0097094 craniofacial suture morphogenesis IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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