ENSG00000164916


Homo sapiens

Features
Gene ID: ENSG00000164916
  
Biological name :FOXK1
  
Synonyms : forkhead box K1 / FOXK1 / P85037
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p22.1
Gene start: 4682309
Gene end: 4771443
  
Corresponding Affymetrix probe sets: 226715_at (Human Genome U133 Plus 2.0 Array)   230342_at (Human Genome U133 Plus 2.0 Array)   235519_at (Human Genome U133 Plus 2.0 Array)   236011_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000328720
Ensembl peptide - ENSP00000475486
NCBI entrez gene - 221937     See in Manteia.
OMIM - 616302
RefSeq - XM_011515191
RefSeq - NM_001037165
RefSeq Peptide - NP_001032242
swissprot - P85037
swissprot - U3KQ26
Ensembl - ENSG00000164916
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxk1ENSDARG00000037872Danio rerio
 FOXK1ENSGALG00000004460Gallus gallus
 Foxk1ENSMUSG00000056493Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOXK2 / Q01167 / forkhead box K2ENSG0000014156848
FOXN3 / O00409 / forkhead box N3ENSG0000005325414
FOXJ2 / Q9P0K8 / forkhead box J2ENSG0000006597013
FOXJ3 / Q9UPW0 / forkhead box J3ENSG0000019881513
FOXN2 / P32314 / forkhead box N2ENSG0000017080213
FOXN4 / Q96NZ1 / forkhead box N4ENSG0000013944513
FOXJ1 / Q92949 / forkhead box J1ENSG0000012965412
FOXN1 / O15353 / forkhead box N1ENSG0000010910112


Protein motifs (from Interpro)
Interpro ID Name
 IPR000253  Forkhead-associated (FHA) domain
 IPR001766  Fork head domain
 IPR008984  SMAD/FHA domain superfamily
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
UCH proteinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100811 YY1 / P25490 / YY1 transcription factor  / complex
 ENSG00000171456 ASXL1 / Q8IXJ9 / additional sex combs like 1, transcriptional regulator  / complex
 ENSG00000163930 BAP1 / Q92560 / BRCA1 associated protein 1  / reaction / complex
 ENSG00000172534 HCFC1 / P51610 / host cell factor C1  / complex
 ENSG00000147162 OGT / O15294 / O-linked N-acetylglucosamine (GlcNAc) transferase  / complex
 ENSG00000143970 ASXL2 / Q76L83 / additional sex combs like 2, transcriptional regulator  / complex






 

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