ENSG00000139445


Homo sapiens

Features
Gene ID: ENSG00000139445
  
Biological name :FOXN4
  
Synonyms : forkhead box N4 / FOXN4 / Q96NZ1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.11
Gene start: 109277979
Gene end: 109309220
  
Corresponding Affymetrix probe sets: 1562695_at (Human Genome U133 Plus 2.0 Array)   1564713_a_at (Human Genome U133 Plus 2.0 Array)   241009_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000474754
Ensembl peptide - ENSP00000299162
Ensembl peptide - ENSP00000347354
Ensembl peptide - ENSP00000408085
NCBI entrez gene - 121643     See in Manteia.
OMIM - 609429
RefSeq - XM_017018819
RefSeq - NM_213596
RefSeq - XM_011537922
RefSeq - XM_011537923
RefSeq - XM_017018818
RefSeq Peptide - NP_998761
swissprot - A0A0C4DG65
swissprot - Q96NZ1
swissprot - S4R3U5
Ensembl - ENSG00000139445
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxn4ENSDARG00000010591Danio rerio
 FOXN4ENSGALG00000005062Gallus gallus
 Foxn4ENSMUSG00000042002Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOXN1 / O15353 / forkhead box N1ENSG0000010910137
FOXK2 / Q01167 / forkhead box K2ENSG0000014156819
FOXJ3 / Q9UPW0 / forkhead box J3ENSG0000019881518
FOXN3 / O00409 / forkhead box N3ENSG0000005325418
FOXJ2 / Q9P0K8 / forkhead box J2ENSG0000006597018
FOXK1 / P85037 / forkhead box K1ENSG0000016491618
FOXN2 / P32314 / forkhead box N2ENSG0000017080217
FOXJ1 / Q92949 / forkhead box J1ENSG0000012965417


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001947 heart looping ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated ISS
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008016 regulation of heart contraction ISS
 biological_processGO:0010842 retina layer formation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035881 amacrine cell differentiation IEA
 biological_processGO:0036302 atrioventricular canal development ISS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0048663 neuron fate commitment IEA
 biological_processGO:0060579 ventral spinal cord interneuron fate commitment IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001158 enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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