ENSG00000136527


Homo sapiens

Features
Gene ID: ENSG00000136527
  
Biological name :TRA2B
  
Synonyms : P62995 / TRA2B / transformer 2 beta homolog
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q27.2
Gene start: 185915906
Gene end: 185938136
  
Corresponding Affymetrix probe sets: 200892_s_at (Human Genome U133 Plus 2.0 Array)   200893_at (Human Genome U133 Plus 2.0 Array)   210180_s_at (Human Genome U133 Plus 2.0 Array)   239447_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000416959
Ensembl peptide - ENSP00000406561
Ensembl peptide - ENSP00000416887
Ensembl peptide - ENSP00000259043
Ensembl peptide - ENSP00000343857
Ensembl peptide - ENSP00000371626
NCBI entrez gene - 6434     See in Manteia.
OMIM - 602719
RefSeq - XM_017007033
RefSeq - NM_001243879
RefSeq - NM_004593
RefSeq - XM_005247703
RefSeq - XM_011513072
RefSeq Peptide - NP_004584
RefSeq Peptide - NP_001230808
swissprot - H7C2L4
swissprot - P62995
swissprot - H7BXF3
Ensembl - ENSG00000136527
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tra2bENSDARG00000002168Danio rerio
 TRA2BENSGALG00000006531Gallus gallus
 Tra2bENSMUSG00000022858Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TRA2A / Q13595 / transformer 2 alpha homologENSG0000016454869
RBMX / P38159 / RNA binding motif protein, X-linkedENSG0000014727430
Q96E39 / RBMXL1 / RNA binding motif protein, X-linked like 1ENSG0000021351628
O75526 / RBMXL2 / RNA binding motif protein, X-linked like 2ENSG0000017074827
P0C7P1 / RBMY1D / RNA binding motif protein, Y-linked, family 1, member DENSG0000024439524
A6NDE4 / RBMY1B / RNA binding motif protein, Y-linked, family 1, member BENSG0000024287524
A6NEQ0 / RBMY1E / RNA binding motif protein, Y-linked, family 1, member EENSG0000024238924
P0DJD3 / RBMY1A1 / RNA binding motif protein, Y-linked, family 1, member A1ENSG0000023441424
Q15415 / RBMY1F / RNA binding motif protein, Y-linked, family 1, member FENSG0000016980024
Q15415 / RBMY1J / RNA binding motif protein, Y-linked, family 1, member JENSG0000022694124
CIRBP / Q14011 / cold inducible RNA binding proteinENSG0000009962222
Q8N7X1 / RBMXL3 / RNA binding motif protein, X-linked like 3ENSG0000017571822
RBM3 / P98179 / RNA binding motif protein 3ENSG0000010231719


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000302 response to reactive oxygen species IEA
 biological_processGO:0000375 RNA splicing, via transesterification reactions TAS
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IMP
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0021796 cerebral cortex regionalization IEA
 biological_processGO:0043484 regulation of RNA splicing IMP
 biological_processGO:0048025 negative regulation of mRNA splicing, via spliceosome IEA
 biological_processGO:0048026 positive regulation of mRNA splicing, via spliceosome IDA
 biological_processGO:0051259 protein complex oligomerization IDA
 biological_processGO:0071333 cellular response to glucose stimulus IMP
 biological_processGO:1990403 embryonic brain development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005637 nuclear inner membrane IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IMP
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IMP
 molecular_functionGO:0003729 mRNA binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0036002 pre-mRNA binding IDA
 molecular_functionGO:0042802 identical protein binding IDA
 molecular_functionGO:0070717 poly-purine tract binding IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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