ENSG00000137124


Homo sapiens

Features
Gene ID: ENSG00000137124
  
Biological name :ALDH1B1
  
Synonyms : aldehyde dehydrogenase 1 family member B1 / ALDH1B1 / P30837
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: p13.1
Gene start: 38392664
Gene end: 38398661
  
Corresponding Affymetrix probe sets: 209645_s_at (Human Genome U133 Plus 2.0 Array)   209646_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000366927
Ensembl peptide - ENSP00000489053
NCBI entrez gene - 219     See in Manteia.
OMIM - 100670
RefSeq - NM_000692
RefSeq - XM_011517802
RefSeq Peptide - NP_000683
swissprot - A0A0U1RQK9
swissprot - P30837
Ensembl - ENSG00000137124
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9CZS1ENSMUSG00000035561Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ALDH2 / P05091 / aldehyde dehydrogenase 2 family (mitochondrial)ENSG0000011127573
O94788 / ALDH1A2 / aldehyde dehydrogenase 1 family member A2ENSG0000012891864
P00352 / ALDH1A1 / aldehyde dehydrogenase 1 family member A1ENSG0000016509262
P47895 / ALDH1A3 / aldehyde dehydrogenase 1 family member A3ENSG0000018425461
O75891 / ALDH1L1 / aldehyde dehydrogenase 1 family member L1ENSG0000014490847
Q3SY69 / ALDH1L2 / aldehyde dehydrogenase 1 family member L2ENSG0000013601047
P49189 / ALDH9A1 / aldehyde dehydrogenase 9 family member A1ENSG0000014314939
AC002996.1ENSG0000025776736
Q9H2A2 / ALDH8A1 / aldehyde dehydrogenase 8 family member A1ENSG0000011851435
P49419 / ALDH7A1 / aldehyde dehydrogenase 7 family member A1ENSG0000016490430


Protein motifs (from Interpro)
Interpro ID Name
 IPR015590  Aldehyde dehydrogenase domain
 IPR016160  Aldehyde dehydrogenase, cysteine active site
 IPR016161  Aldehyde/histidinol dehydrogenase
 IPR016162  Aldehyde dehydrogenase, N-terminal
 IPR029510  Aldehyde dehydrogenase, glutamic acid active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process NAS
 biological_processGO:0006068 ethanol catabolic process IEA
 biological_processGO:0006069 ethanol oxidation TAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0004029 aldehyde dehydrogenase (NAD) activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0051287 NAD binding ISS


Pathways (from Reactome)
Pathway description
Ethanol oxidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000137124 P30837 / ALDH1B1 / aldehyde dehydrogenase 1 family member B1  / complex






 

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