ENSG00000138668


Homo sapiens

Features
Gene ID: ENSG00000138668
  
Biological name :HNRNPD
  
Synonyms : heterogeneous nuclear ribonucleoprotein D / HNRNPD / Q14103
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q21.22
Gene start: 82352498
Gene end: 82374503
  
Corresponding Affymetrix probe sets: 200073_s_at (Human Genome U133 Plus 2.0 Array)   209330_s_at (Human Genome U133 Plus 2.0 Array)   213359_at (Human Genome U133 Plus 2.0 Array)   221480_at (Human Genome U133 Plus 2.0 Array)   221481_x_at (Human Genome U133 Plus 2.0 Array)   227744_s_at (Human Genome U133 Plus 2.0 Array)   229129_at (Human Genome U133 Plus 2.0 Array)   239040_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000305860
Ensembl peptide - ENSP00000426666
Ensembl peptide - ENSP00000426446
Ensembl peptide - ENSP00000425439
Ensembl peptide - ENSP00000424002
Ensembl peptide - ENSP00000422615
Ensembl peptide - ENSP00000421952
Ensembl peptide - ENSP00000420926
Ensembl peptide - ENSP00000313327
Ensembl peptide - ENSP00000313199
NCBI entrez gene - 3184     See in Manteia.
OMIM - 601324
RefSeq - NM_002138
RefSeq - NM_031369
RefSeq - NM_031370
RefSeq - NM_001003810
RefSeq Peptide - NP_002129
RefSeq Peptide - NP_112737
RefSeq Peptide - NP_112738
RefSeq Peptide - NP_001003810
swissprot - H0YA96
swissprot - D6RF44
swissprot - Q14103
swissprot - D6RD83
swissprot - D6RBQ9
swissprot - D6RBP9
swissprot - D6RAF8
swissprot - A0A024RDF4
swissprot - A0A024RDF3
swissprot - A0A024RDB4
swissprot - H0Y8G5
Ensembl - ENSG00000138668
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hnrnpdENSDARG00000059246Danio rerio
 HNRNPDENSGALG00000011184Gallus gallus
 HnrnpdENSMUSG00000000568Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q99729 / HNRNPAB / heterogeneous nuclear ribonucleoprotein A/BENSG0000019745162
O14979 / HNRNPDL / heterogeneous nuclear ribonucleoprotein D likeENSG0000015279557
MSI2 / Q96DH6 / musashi RNA binding protein 2ENSG0000015394433
MSI1 / O43347 / musashi RNA binding protein 1ENSG0000013509730
Q13148 / TARDBP / TAR DNA binding proteinENSG0000012094827
DAZAP1 / Q96EP5 / DAZ associated protein 1ENSG0000007162626


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR012956  CARG-binding factor, N-terminal
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0001889 liver development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006396 RNA processing TAS
 biological_processGO:0006401 RNA catabolic process TAS
 biological_processGO:0007420 brain development IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0016070 RNA metabolic process TAS
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0032204 regulation of telomere maintenance ISS
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0042752 regulation of circadian rhythm IMP
 biological_processGO:0043488 regulation of mRNA stability TAS
 biological_processGO:0045727 positive regulation of translation IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated NAS
 biological_processGO:0048255 mRNA stabilization IEA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0051592 response to calcium ion IEA
 biological_processGO:0051602 response to electrical stimulus IEA
 biological_processGO:0061158 3"-UTR-mediated mRNA destabilization IEA
 biological_processGO:0071230 cellular response to amino acid stimulus IEA
 biological_processGO:0071392 cellular response to estradiol stimulus IEA
 biological_processGO:0071732 cellular response to nitric oxide IEA
 biological_processGO:0097167 circadian regulation of translation IMP
 biological_processGO:1901355 response to rapamycin IEA
 biological_processGO:1904355 positive regulation of telomere capping ISS
 biological_processGO:1904383 response to sodium phosphate IEA
 biological_processGO:1904586 cellular response to putrescine IEA
 biological_processGO:1905663 positive regulation of telomerase RNA reverse transcriptase activity ISS
 biological_processGO:1990828 hepatocyte dedifferentiation IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003680 AT DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0035925 mRNA 3"-UTR AU-rich region binding IEA
 molecular_functionGO:0042162 telomeric DNA binding IDA
 molecular_functionGO:0042826 histone deacetylase binding IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000138668 HNRNPD / Q14103 / heterogeneous nuclear ribonucleoprotein D  / complex / reaction






 

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