ENSG00000138942


Homo sapiens

Features
Gene ID: ENSG00000138942
  
Biological name :RNF185
  
Synonyms : Q96GF1 / ring finger protein 185 / RNF185
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q12.2
Gene start: 31160183
Gene end: 31207019
  
Corresponding Affymetrix probe sets: 224750_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000266252
Ensembl peptide - ENSP00000427755
Ensembl peptide - ENSP00000410916
Ensembl peptide - ENSP00000320508
NCBI entrez gene - 91445     See in Manteia.
RefSeq - NM_152267
RefSeq - NM_001135825
RefSeq Peptide - NP_001129297
RefSeq Peptide - NP_689480
swissprot - Q96GF1
swissprot - A0A024R1H4
swissprot - A0A024R1F5
swissprot - A9X3U0
Ensembl - ENSG00000138942
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SYNJ2 / O15056 / synaptojanin 2ENSG0000007826924
SYNJ1 / O43426 / synaptojanin 1ENSG0000015908222
INPP5B / P32019 / inositol polyphosphate-5-phosphatase BENSG0000020408418
INPPL1 / O15357 / inositol polyphosphate phosphatase like 1ENSG0000016545818
OCRL / Q01968 / OCRL, inositol polyphosphate-5-phosphataseENSG0000012212617
INPP5D / Q92835 / inositol polyphosphate-5-phosphatase DENSG0000016891816
INPP5E / Q9NRR6 / inositol polyphosphate-5-phosphatase EENSG0000014838414
INPP5J / Q15735 / inositol polyphosphate-5-phosphatase JENSG0000018513314
INPP5K / Q9BT40 / inositol polyphosphate-5-phosphatase KENSG0000013237610


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR018957  Zinc finger, C3HC4 RING-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IMP
 biological_processGO:0036503 ERAD pathway IGI
 biological_processGO:0051865 protein autoubiquitination IDA
 biological_processGO:0055085 transmembrane transport TAS
 biological_processGO:0071712 ER-associated misfolded protein catabolic process IBA
 biological_processGO:1904380 endoplasmic reticulum mannose trimming TAS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0036513 Derlin-1 retrotranslocation complex IDA
 cellular_componentGO:0044322 endoplasmic reticulum quality control compartment IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0044390 ubiquitin-like protein conjugating enzyme binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
ABC-family proteins mediated transport
Defective CFTR causes cystic fibrosis
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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