ENSG00000140945


Homo sapiens

Features
Gene ID: ENSG00000140945
  
Biological name :CDH13
  
Synonyms : cadherin 13 / CDH13 / P55290
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q23.3
Gene start: 82626803
Gene end: 83800640
  
Corresponding Affymetrix probe sets: 204726_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000479395
Ensembl peptide - ENSP00000457149
Ensembl peptide - ENSP00000457914
Ensembl peptide - ENSP00000268613
Ensembl peptide - ENSP00000394557
Ensembl peptide - ENSP00000408632
Ensembl peptide - ENSP00000442225
Ensembl peptide - ENSP00000455781
Ensembl peptide - ENSP00000456297
Ensembl peptide - ENSP00000456491
NCBI entrez gene - 1012     See in Manteia.
OMIM - 601364
RefSeq - XM_017022849
RefSeq - NM_001220488
RefSeq - NM_001220489
RefSeq - NM_001220490
RefSeq - NM_001220491
RefSeq - NM_001220492
RefSeq - NM_001257
RefSeq - XM_011522804
RefSeq Peptide - NP_001248
RefSeq Peptide - NP_001207417
RefSeq Peptide - NP_001207418
RefSeq Peptide - NP_001207419
RefSeq Peptide - NP_001207420
RefSeq Peptide - NP_001207421
swissprot - H3BRL7
swissprot - P55290
swissprot - F5H7W7
swissprot - H3BTF2
swissprot - H3BV21
swissprot - H3BQH4
Ensembl - ENSG00000140945
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdh13ENSDARG00000014215Danio rerio
 CDH13ENSGALG00000005483Gallus gallus
 Cdh13ENSMUSG00000031841Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDH2 / P19022 / cadherin 2ENSG0000017055838
CDH4 / P55283 / cadherin 4ENSG0000017924236
CDH1 / P12830 / cadherin 1ENSG0000003906835
CDH3 / P22223 / cadherin 3ENSG0000006203832
DSC3 / Q14574 / desmocollin 3ENSG0000013476231
DSC2 / Q02487 / desmocollin 2ENSG0000013475530
CDH15 / P55291 / cadherin 15ENSG0000012991029
DSC1 / Q08554 / desmocollin 1ENSG0000013476528
CDH26 / Q8IXH8 / cadherin 26ENSG0000012421526


Protein motifs (from Interpro)
Interpro ID Name
 IPR002126  Cadherin
 IPR014868  Cadherin prodomain
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site
 IPR033216  Cadherin-13


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IMP
 biological_processGO:0001954 positive regulation of cell-matrix adhesion IMP
 biological_processGO:0002040 sprouting angiogenesis IDA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IDA
 biological_processGO:0007162 negative regulation of cell adhesion IDA
 biological_processGO:0007266 Rho protein signal transduction IMP
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0010033 response to organic substance IEA
 biological_processGO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IDA
 biological_processGO:0016601 Rac protein signal transduction IMP
 biological_processGO:0030032 lamellipodium assembly IDA
 biological_processGO:0030100 regulation of endocytosis IMP
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0034332 adherens junction organization TAS
 biological_processGO:0042058 regulation of epidermal growth factor receptor signaling pathway IMP
 biological_processGO:0043542 endothelial cell migration IDA
 biological_processGO:0043616 keratinocyte proliferation IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IMP
 biological_processGO:0050850 positive regulation of calcium-mediated signaling IDA
 biological_processGO:0050927 positive regulation of positive chemotaxis IDA
 biological_processGO:0051668 localization within membrane IMP
 biological_processGO:0055096 low-density lipoprotein particle mediated signaling IDA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005901 caveola IDA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031012 extracellular matrix IDA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0043005 neuron projection IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0030169 low-density lipoprotein particle binding IDA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0055100 adiponectin binding ISS
 molecular_functionGO:0071813 lipoprotein particle binding IDA


Pathways (from Reactome)
Pathway description
Adherens junctions interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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