ENSG00000141338


Homo sapiens

Features
Gene ID: ENSG00000141338
  
Biological name :ABCA8
  
Synonyms : ABCA8 / ATP binding cassette subfamily A member 8 / O94911
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q24.2
Gene start: 68867292
Gene end: 68955392
  
Corresponding Affymetrix probe sets: 1565778_at (Human Genome U133 Plus 2.0 Array)   1565780_at (Human Genome U133 Plus 2.0 Array)   204719_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466126
Ensembl peptide - ENSP00000402814
Ensembl peptide - ENSP00000467186
Ensembl peptide - ENSP00000481467
Ensembl peptide - ENSP00000467271
Ensembl peptide - ENSP00000269080
NCBI entrez gene - 10351     See in Manteia.
OMIM - 612505
RefSeq - XM_011524192
RefSeq - NM_001288985
RefSeq - NM_001288986
RefSeq - NM_007168
RefSeq - XM_005256938
RefSeq - XM_005256940
RefSeq - XM_011524191
RefSeq Peptide - NP_001275914
RefSeq Peptide - NP_001275915
RefSeq Peptide - NP_009099
swissprot - A0A0A0MSU4
swissprot - A0A075B774
swissprot - K7ELK9
swissprot - O94911
swissprot - Q49AI9
swissprot - A0A024R8L6
Ensembl - ENSG00000141338
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000021399Gallus gallus
 ENSGALG00000021395Gallus gallus
 Abca8bENSMUSG00000020620Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ABCA9 / Q8IUA7 / ATP binding cassette subfamily A member 9ENSG0000015425872
ABCA6 / Q8N139 / ATP binding cassette subfamily A member 6ENSG0000015426259
ABCA10 / Q8WWZ4 / ATP binding cassette subfamily A member 10ENSG0000015426358
ABCA5 / Q8WWZ7 / ATP binding cassette subfamily A member 5ENSG0000015426542
ABCA4 / P78363 / ATP binding cassette subfamily A member 4ENSG0000019869126
ABCA2 / Q9BZC7 / ATP binding cassette subfamily A member 2ENSG0000010733126
ABCA1 / O95477 / ATP binding cassette subfamily A member 1ENSG0000016502926
ABCA7 / Q8IZY2 / ATP binding cassette subfamily A member 7ENSG0000006468726
ABCA13 / Q86UQ4 / ATP binding cassette subfamily A member 13ENSG0000017986925
ABCA12 / Q86UK0 / ATP binding cassette subfamily A member 12ENSG0000014445224
ABCA3 / Q99758 / ATP binding cassette subfamily A member 3ENSG0000016797224


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR017871  ABC transporter, conserved site
 IPR026082  ABC transporter A
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006855 drug transmembrane transport IEA
 biological_processGO:0006869 lipid transport IBA
 biological_processGO:0042908 xenobiotic transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008559 xenobiotic transmembrane transporting ATPase activity TAS
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA


Pathways (from Reactome)
Pathway description
ABC-family proteins mediated transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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