ENSG00000148584


Homo sapiens

Features
Gene ID: ENSG00000148584
  
Biological name :A1CF
  
Synonyms : A1CF / APOBEC1 complementation factor / Q9NQ94
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q11.23
Gene start: 50799409
Gene end: 50885675
  
Corresponding Affymetrix probe sets: 220951_s_at (Human Genome U133 Plus 2.0 Array)   241547_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000363113
Ensembl peptide - ENSP00000378868
Ensembl peptide - ENSP00000397953
Ensembl peptide - ENSP00000378873
Ensembl peptide - ENSP00000282641
Ensembl peptide - ENSP00000363105
Ensembl peptide - ENSP00000363107
Ensembl peptide - ENSP00000363109
NCBI entrez gene - 29974     See in Manteia.
RefSeq - XM_017016160
RefSeq - NM_001198818
RefSeq - NM_001198819
RefSeq - NM_001198820
RefSeq - NM_014576
RefSeq - NM_138932
RefSeq - NM_138933
RefSeq - XM_005269718
RefSeq - XM_005269720
RefSeq - XM_011539729
RefSeq - XM_011539730
RefSeq Peptide - NP_001185747
RefSeq Peptide - NP_001185749
RefSeq Peptide - NP_055391
RefSeq Peptide - NP_620310
RefSeq Peptide - NP_620311
RefSeq Peptide - NP_001185748
swissprot - Q9NQ94
swissprot - A0A024QZI9
swissprot - A0A024QZM7
swissprot - A0A024QZJ5
swissprot - F8W9F8
swissprot - Q5T0W7
Ensembl - ENSG00000148584
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 a1cfENSDARG00000002968Danio rerio
 A1CFENSGALG00000003765Gallus gallus
 A1cfENSMUSG00000052595Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RBM47 / A0AV96 / RNA binding motif protein 47ENSG0000016369446
RBM46 / Q8TBY0 / RNA binding motif protein 46ENSG0000015196245
HNRNPR / O43390 / heterogeneous nuclear ribonucleoprotein RENSG0000012594433
O60506 / SYNCRIP / synaptotagmin binding cytoplasmic RNA interacting proteinENSG0000013531632
DND1 / Q8IYX4 / DND microRNA-mediated repression inhibitor 1ENSG0000025645319


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR006535  HnRNP R/Q splicing factor
 IPR033111  APOBEC1 complementation factor
 IPR034435  Probable RNA-binding protein 46, RNA recognition motif 2
 IPR034538  ACF, RNA recognition motif 1
 IPR034539  ACF, RNA recognition motif 3
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007566 embryo implantation IEA
 biological_processGO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression IEA
 biological_processGO:0016554 cytidine to uridine editing TAS
 biological_processGO:0016556 mRNA modification IEA
 biological_processGO:0050821 protein stabilization IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0030895 apolipoprotein B mRNA editing enzyme complex IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003727 single-stranded RNA binding IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
mRNA Editing: C to U Conversion
Formation of the Editosome


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000111701 P41238 / APOBEC1 / apolipoprotein B mRNA editing enzyme catalytic subunit 1  / reaction / complex






 

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