ENSG00000152484


Homo sapiens

Features
Gene ID: ENSG00000152484
  
Biological name :USP12
  
Synonyms : O75317 / ubiquitin specific peptidase 12 / USP12
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q12.13
Gene start: 27066142
Gene end: 27171896
  
Corresponding Affymetrix probe sets: 213327_s_at (Human Genome U133 Plus 2.0 Array)   215886_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000282344
Ensembl peptide - ENSP00000480395
Ensembl peptide - ENSP00000478929
NCBI entrez gene - 219333     See in Manteia.
OMIM - 603091
RefSeq - XM_005266282
RefSeq - XM_017020416
RefSeq - NM_182488
RefSeq - XM_011534956
RefSeq Peptide - NP_872294
swissprot - O75317
swissprot - A0A087WWP2
swissprot - A0A087WUU2
Ensembl - ENSG00000152484
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A4FUN7ENSDARG00000078109Danio rerio
 USP12ENSGALG00000034708Gallus gallus
 Usp12ENSMUSG00000029640Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
USP46 / P62068 / ubiquitin specific peptidase 46ENSG0000010918988
USP38 / Q8NB14 / ubiquitin specific peptidase 38ENSG0000017018532
USP35 / Q9P2H5 / ubiquitin specific peptidase 35ENSG0000011836931


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IDA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IMP
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity TAS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0101005 ubiquitinyl hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000140153 WDR20 / Q8TBZ3 / WD repeat domain 20  / complex
 ENSG00000169083 AR / P10275 / androgen receptor  / complex
 ENSG00000114742 WDR48 / Q8TAF3 / WD repeat domain 48  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr