ENSG00000158022


Homo sapiens

Features
Gene ID: ENSG00000158022
  
Biological name :TRIM63
  
Synonyms : Q969Q1 / TRIM63 / tripartite motif containing 63
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.11
Gene start: 26051304
Gene end: 26068436
  
Corresponding Affymetrix probe sets: 236972_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000363390
NCBI entrez gene - 84676     See in Manteia.
OMIM - 606131
RefSeq - NM_032588
RefSeq - XM_017002559
RefSeq Peptide - NP_115977
swissprot - Q969Q1
Ensembl - ENSG00000158022
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trim63aENSDARG00000028027Danio rerio
 trim63bENSDARG00000086685Danio rerio
 TRIM63ENSGALG00000034107Gallus gallus
 Trim63ENSMUSG00000028834Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BYV6 / TRIM55 / tripartite motif containing 55ENSG0000014757360
Q9BYV2 / TRIM54 / tripartite motif containing 54ENSG0000013810058
Q7Z4K8 / TRIM46 / tripartite motif containing 46ENSG0000016346231
Q9NQ86 / TRIM36 / tripartite motif containing 36ENSG0000015250329
MID1 / O15344 / midline 1ENSG0000010187128
Q6ZTA4 / TRIM67 / tripartite motif containing 67ENSG0000011928327
MID2 / Q9UJV3 / midline 2ENSG0000008056127
TRIM9 / Q9C026 / tripartite motif containing 9ENSG0000010050525
FSD1L / Q9BXM9 / fibronectin type III and SPRY domain containing 1 likeENSG0000010670116
FSD1 / Q9BTV5 / fibronectin type III and SPRY domain containing 1ENSG0000010525514


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017903  COS domain
 IPR017907  Zinc finger, RING-type, conserved site
 IPR027370  RING-type zinc-finger, LisH dimerisation motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction IEA
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0010614 negative regulation of cardiac muscle hypertrophy IEA
 biological_processGO:0014732 skeletal muscle atrophy IEA
 biological_processGO:0014878 response to electrical stimulus involved in regulation of muscle adaptation IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0051384 response to glucocorticoid IEA
 biological_processGO:0070555 response to interleukin-1 IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005874 microtubule NAS
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0031430 M band IEA
 cellular_componentGO:0043292 contractile fiber IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031432 titin binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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