ENSG00000162517


Homo sapiens

Features
Gene ID: ENSG00000162517
  
Biological name :PEF1
  
Synonyms : PEF1 / penta-EF-hand domain containing 1 / Q9UBV8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p35.2
Gene start: 31629862
Gene end: 31644896
  
Corresponding Affymetrix probe sets: 217923_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362807
NCBI entrez gene - 553115     See in Manteia.
OMIM - 610033
RefSeq - XM_017001681
RefSeq - NM_012392
RefSeq - XM_011541747
RefSeq - XM_017001680
RefSeq - XM_011541745
RefSeq - XM_011541746
RefSeq Peptide - NP_036524
swissprot - Q9UBV8
Ensembl - ENSG00000162517
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pef1ENSDARG00000023989Danio rerio
 PEF1ENSGALG00000040519Gallus gallus
 Pef1ENSMUSG00000028779Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDCD6 / O75340 / programmed cell death 6ENSG0000024991529
SRI / P30626 / sorcinENSG0000007514228
GCA / P28676 / grancalcinENSG0000011527127
CAPNS1 / P04632 / calpain small subunit 1ENSG0000012624724
CAPNS2 / Q96L46 / calpain small subunit 2ENSG0000025681220


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IMP
 biological_processGO:0014029 neural crest formation IMP
 biological_processGO:0014032 neural crest cell development IMP
 biological_processGO:0048208 COPII vesicle coating IMP
 biological_processGO:0051592 response to calcium ion IPI
 biological_processGO:1902527 positive regulation of protein monoubiquitination IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0012507 ER to Golgi transport vesicle membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030127 COPII vesicle coat IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004198 calcium-dependent cysteine-type endopeptidase activity IBA
 molecular_functionGO:0005509 calcium ion binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0046983 protein dimerization activity IPI
 molecular_functionGO:0048306 calcium-dependent protein binding IPI
 molecular_functionGO:0060090 molecular adaptor activity IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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