ENSG00000165568


Homo sapiens

Features
Gene ID: ENSG00000165568
  
Biological name :AKR1E2
  
Synonyms : AKR1E2 / aldo-keto reductase family 1 member E2 / Q96JD6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: p15.1
Gene start: 4786629
Gene end: 4848062
  
Corresponding Affymetrix probe sets: 1555220_a_at (Human Genome U133 Plus 2.0 Array)   1559982_s_at (Human Genome U133 Plus 2.0 Array)   223856_at (Human Genome U133 Plus 2.0 Array)   244393_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000435436
Ensembl peptide - ENSP00000434437
Ensembl peptide - ENSP00000436794
Ensembl peptide - ENSP00000298375
Ensembl peptide - ENSP00000335034
Ensembl peptide - ENSP00000335603
Ensembl peptide - ENSP00000431625
Ensembl peptide - ENSP00000432947
Ensembl peptide - ENSP00000433496
NCBI entrez gene - 83592     See in Manteia.
OMIM - 617451
RefSeq - XM_017016745
RefSeq - XM_011519718
RefSeq - XM_011519719
RefSeq - XM_011519720
RefSeq - XM_011519722
RefSeq - XM_011519724
RefSeq - XM_011519725
RefSeq - XM_011519729
RefSeq - XM_017016744
RefSeq - NM_001040177
RefSeq - NM_001271021
RefSeq - NM_001271025
RefSeq - XM_011519715
RefSeq Peptide - NP_001257954
RefSeq Peptide - NP_001035267
RefSeq Peptide - NP_001257950
swissprot - G3V1C1
swissprot - E9PK93
swissprot - Q96JD6
swissprot - H0YCI2
swissprot - H0YDE8
Ensembl - ENSG00000165568
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 akr1b1ENSDARG00000006215Danio rerio
 si:dkey-180p18.9ENSDARG00000045598Danio rerio
 ENSGALG00000013058Gallus gallus
 ENSGALG00000019284Gallus gallus
 AKR1B10L1ENSGALG00000045122Gallus gallus
 AKR1B10L2ENSGALG00000013072Gallus gallus
 AKR1E2ENSGALG00000003466Gallus gallus
 Akr1e1ENSMUSG00000045410Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AKR1B1 / P15121 / aldo-keto reductase family 1 member BENSG0000008566257
O60218 / AKR1B10 / aldo-keto reductase family 1 member B10ENSG0000019807455
C9JRZ8 / AKR1B15 / aldo-keto reductase family 1 member B15ENSG0000022747154
AKR1D1 / P51857 / aldo-keto reductase family 1 member D1ENSG0000012278746
AKR1C4 / P17516 / aldo-keto reductase family 1 member C4ENSG0000019861045
AKR1C3 / P42330 / aldo-keto reductase family 1 member C3ENSG0000019613943
AKR1C2 / P52895 / aldo-keto reductase family 1 member C2ENSG0000015163243
AKR1C1 / Q04828 / aldo-keto reductase family 1 member C1ENSG0000018713443
AKR1A1 / P14550 / aldo-keto reductase family 1 member A1ENSG0000011744842


Protein motifs (from Interpro)
Interpro ID Name
 IPR018170  Aldo/keto reductase, conserved site
 IPR020471  Aldo/keto reductase
 IPR023210  NADP-dependent oxidoreductase domain
 IPR036812  NADP-dependent oxidoreductase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0016491 oxidoreductase activity IDA
 molecular_functionGO:0050571 1,5-anhydro-D-fructose reductase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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