ENSG00000198074


Homo sapiens

Features
Gene ID: ENSG00000198074
  
Biological name :AKR1B10
  
Synonyms : AKR1B10 / aldo-keto reductase family 1 member B10 / O60218
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q33
Gene start: 134527592
Gene end: 134541408
  
Corresponding Affymetrix probe sets: 206561_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000352584
NCBI entrez gene - 57016     See in Manteia.
OMIM - 604707
RefSeq - NM_020299
RefSeq - XM_011516416
RefSeq Peptide - NP_064695
swissprot - O60218
Ensembl - ENSG00000198074
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 akr1b1ENSDARG00000006215Danio rerio
 si:dkey-180p18.9ENSDARG00000045598Danio rerio
 Akr1b10ENSMUSG00000061758Mus musculus
 Akr1b7ENSMUSG00000052131Mus musculus
 Akr1b8ENSMUSG00000029762Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
C9JRZ8 / AKR1B15 / aldo-keto reductase family 1 member B15ENSG0000022747186
AKR1B1 / P15121 / aldo-keto reductase family 1 member BENSG0000008566271
AKR1E2 / Q96JD6 / aldo-keto reductase family 1 member E2ENSG0000016556856
AKR1D1 / P51857 / aldo-keto reductase family 1 member D1ENSG0000012278751
AKR1A1 / P14550 / aldo-keto reductase family 1 member A1ENSG0000011744851
AKR1C2 / P52895 / aldo-keto reductase family 1 member C2ENSG0000015163249
AKR1C4 / P17516 / aldo-keto reductase family 1 member C4ENSG0000019861048
AKR1C1 / Q04828 / aldo-keto reductase family 1 member C1ENSG0000018713448
AKR1C3 / P42330 / aldo-keto reductase family 1 member C3ENSG0000019613947


Protein motifs (from Interpro)
Interpro ID Name
 IPR018170  Aldo/keto reductase, conserved site
 IPR020471  Aldo/keto reductase
 IPR023210  NADP-dependent oxidoreductase domain
 IPR036812  NADP-dependent oxidoreductase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001523 retinoid metabolic process TAS
 biological_processGO:0016488 farnesol catabolic process IDA
 biological_processGO:0044597 daunorubicin metabolic process IMP
 biological_processGO:0044598 doxorubicin metabolic process IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001758 retinal dehydrogenase activity IDA
 molecular_functionGO:0004033 aldo-keto reductase (NADP) activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0045550 geranylgeranyl reductase activity IDA
 molecular_functionGO:0047718 indanol dehydrogenase activity IDA


Pathways (from Reactome)
Pathway description
Retinoid metabolism and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000114113 RBP2 / P50120 / retinol binding protein 2  / reaction






 

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